IDO1-mediated tryptophan depletion potently inhibits CAR-T functionality as part of a CAR-T driven adaptive immune resistance response in the tumor microenvironment

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作者
Thomas, Evan P. [1 ]
Jessup, Heidi K. [1 ]
Qin, Jim [1 ]
Baturevych, Alex [1 ]
Swanson, Christina [1 ]
Swenson, Sarah [1 ]
Prentice, Ken [1 ]
Levitsky, Hyam [1 ]
Ports, Michael [1 ]
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[1] Juno Therapeut, Seattle, WA USA
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R73 [肿瘤学];
学科分类号
100214 ;
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P199
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页数:2
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