The conundrum of using hyperoxia in COVID-19 treatment strategies: may intermittent therapeutic hyperoxia play a helpful role in the expression of the surface receptors ACE2 and Furin in lung tissue via triggering of HIF-1α?

被引:9
|
作者
Koch, Andreas [1 ,2 ]
Kaehler, Wataru [1 ,2 ]
Klapa, Sebastian [1 ,2 ]
Grams, Bente [1 ,2 ]
van Ooij, Pieter- Jan A. M. [3 ,4 ]
机构
[1] Naval Inst Maritime Med, Joint Sect Maritime Med, Kiel, Germany
[2] Univ Kiel, Joint Sect Maritime Med, Kiel, Germany
[3] Royal Netherlands Navy, Diving Med Ctr, Den Helder, Netherlands
[4] Acad Med Ctr, Resp Dept, Amsterdam, Netherlands
关键词
RENIN-ANGIOTENSIN SYSTEM; CONVERTING ENZYME-2; OXYGEN; HYPOXIA; CELLS;
D O I
10.1186/s40635-020-00323-1
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
[No abstract available]
引用
收藏
页数:6
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  • [1] The conundrum of using hyperoxia in COVID-19 treatment strategies: may intermittent therapeutic hyperoxia play a helpful role in the expression of the surface receptors ACE2 and Furin in lung tissue via triggering of HIF-1α?
    Andreas Koch
    Wataru Kähler
    Sebastian Klapa
    Bente Grams
    Pieter- Jan A. M. van Ooij
    Intensive Care Medicine Experimental, 8