Complex Regional Pain Syndrome, Current Concepts and Treatment Options

被引：62

作者：

Urits, Ivan ^{[1
]}

Shen, Abra H. ^{[2
]}

Jones, Mark R. ^{[1
]}

Viswanath, Omar ^{[1
]}

Kaye, Alan D. ^{[3
]}

机构：

[1] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Anesthesiol Crit Care & Pain Med, Boston, MA USA

[2] Harvard Med Sch, Boston, MA USA

[3] Lousiana State Univ, Hlth Sci Ctr, Dept Anesthesiol, 1542 Tulane Ave,Suite 659, New Orleans, LA 70112 USA

来源：

CURRENT PAIN AND HEADACHE REPORTS | 2018年 / 22卷 / 02期

关键词：

Complex regional pain syndrome; CRPS-1; Disproportionate pain; Allodynia; Hyperalgesia; Budapest criteria; Spinal cord stimulation; SYNDROME TYPE-I; SPINAL-CORD STIMULATION; INTRAVENOUS IMMUNOGLOBULIN TREATMENT; ADJUVANT PHYSICAL-THERAPY; SYNDROME TYPE-1 CRPS1; INTRATHECAL BACLOFEN; VITAMIN-C; PSYCHOLOGICAL-FACTORS; OCCUPATIONAL-THERAPY; DIAGNOSTIC-CRITERIA;

D O I：

10.1007/s11916-018-0667-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose of Review Complex regional pain syndrome (CRPS) refers to a chronic pain condition that is characterized by progressively worsening spontaneous regional pain without dermatomal distribution. The symptomatology includes pain out of proportion in time and severity to the inciting event. The purpose of this review is to present the most current information concerning epidemiology, diagnosis, pathophysiology, and therapy for CRPS. Recent Findings In recent years, discovery of pathophysiologic mechanisms of CRPS has led to significant strides in the understanding of the disease process. Summary Continued elucidation of the underlying pathophysiological mechanisms will allow for the development of more targeted and effective evidence-based therapy protocols. Further large clinical trials are needed to investigate mechanisms and treatment of the disorder.

引用

页数：9

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