The periplasmic folding of a cysteineless autotransporter passenger domain interferes with its outer membrane translocation

被引：25

作者：

Rutherford, Nancy

Charbonneau, Marie-Eve

Berthiaume, Frederic

Betton, Jean-Michel

Mourez, Michael

机构：

[1] Univ Montreal, Fac Med Vet, Canada Res Chair Bacterial Anim Dis, St Hyacinthe, PQ J2S 7C6, Canada

[2] Inst Pasteur, CNRS, URA 2185, F-75724 Paris 15, France

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 11期

关键词：

D O I：

10.1128/JB.01949-05

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Autotransporters are single polypeptides consisting of an outer membrane translocation domain mediating the translocation of a passenger domain. The periplasmic folding state of the passenger domain is controversial. By comparisons of passenger domains differing in their folding properties, our results suggest that periplasmic folding of passenger domains interferes with translocation.

引用

页码：4111 / 4116

页数：6

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