Association of serum copper levels and glycemic control in patients with type 2 diabetes

被引：0
|
作者：
Naka, Toyoko [1 ]
Kaneto, Hideaki [1 ]
Katakami, Naoto [1 ]
Matsuoka, Taka-aki [1 ]
Harada, Ayako [1 ]
Yamasaki, Yoshimitsu [1 ]
Matsuhisa, Munehide [2 ]
Shimomura, Iichiro [1 ]
机构：
[1] Osaka Univ, Grad Sch Med, Dept Metab Med, Suita, Osaka 5650871, Japan
[2] Univ Tokushima, Diabet Therapeut & Res Ctr, Tokushima 770, Japan
来源：
ENDOCRINE JOURNAL | 2013年 / 60卷 / 03期
关键词：
Copper; Type; 2; diabetes; Hemoglobin A1c (HbA1c); DISEASE; ZINC; MAGNESIUM;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It has been suggested that copper ion is involved in the pathogenesis of various diseases. The aim of this study is to examine the association of serum copper levels and glycemic control in patients with type 2 diabetes. We recruited a total of 132 patients with type 2 diabetes, and measured their serum copper levels by atomic absorption spectrometry. Serum copper levels were positively correlated with HbA1c levels (r=0.176, p=0.044). In addition, after 3-month glycemic control, we evaluated whether the improvement of glycemic control influenced serum copper levels. As hemoglobin A1c (HbA1c) levels were decreased (from 8.7% to 6.8%, p<0.001), copper levels tended to be decreased (from 105.7 mu g/dL, to 101.8 mu g/dL, p=0.069). In conclusion, it is likely that serum copper levels are associated with glycemic control in patients with type 2 diabetes.
引用
收藏
页码：393 / 396
页数：4
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