Para-chlorobenzyl protecting groups as stabilizers of the glycosidic linkage: Synthesis of the 3'-O-sulfated Lewis X trisaccharide

被引：32
|
作者：
Pohl, NL [1 ]
Kiessling, LL [1 ]
机构：
[1] UNIV WISCONSIN,DEPT CHEM,MADISON,WI 53706
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 40期
关键词：
D O I：
10.1016/S0040-4039(97)01670-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The 3'-0-sulfated trisaccharide Lewis x (1) and unsulfated Lewis x (2) have been synthesized using a mute that highlights a more facile regioselective benzylidene ring-opening procedure and the employment of chlorobenzyl groups as a way of strengthening the acid-labile alpha-fucose linkage. (C) 1997 Elsevier Science Ltd.
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页码：6985 / 6988
页数：4
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