A systematic review on phytochemicals for the treatment of dengue

被引:12
|
作者
Ali, Faraat [1 ]
Chorsiya, Anushma [2 ]
Anjum, Varisha [3 ]
Khasimbi, Shaik [4 ]
Ali, Asad [5 ]
机构
[1] Botswana Med Regulatory Author, Dept Inspect & Licensing, Lab Serv, Gaborone, Botswana
[2] Delhi Pharmaceut Sci & Res Univ, Sch Pharmaceut Sci, New Delhi, India
[3] Jamia Hamdard, Dept Pharmacognosy & Phytochem, Fac Pharm, New Delhi, India
[4] Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut Chem, New Delhi, India
[5] Jamia Hamdard, Sch Chem & Life Sci, Dept Chem, New Delhi, India
关键词
crude extracts; dengue fever; essential oils; natural products; phytochemicals; AEDES-AEGYPTI L; MOSQUITO LARVICIDAL ACTIVITY; ENVELOPE DOMAIN-III; IN-VITRO; ANTIVIRAL ACTIVITY; ESSENTIAL OILS; VIRUS-INFECTION; NS3; HELICASE; IMMUNOMODULATORY ACTIVITY; SULFATED POLYSACCHARIDES;
D O I
10.1002/ptr.6917
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Dengue fever is prevalent in subtopic regions, producing mortality and morbidity worldwide, which have been of major concern to different governments and World Health Organization. The search of new anti-dengue agents from phytochemicals was assumed to be highly emergent in past. The phytochemicals have been used in wide distribution of vector ailments such as malaria. The demand of the phytochemicals is based on the medicines which are mostly considered to be safer, less harmful than synthetic drugs and nontoxic. This review mentions majorly about the phytochemicals potentially inhibiting dengue fever around the world. The phytochemicals have been isolated from different species, have potential for the treatment of dengue. Different crude extracts and essential oils obtained from different species showed a broad activity against different phytochemicals. The current studies showed that natural products represent a rich source of medicines toward the dengue fever. Furthermore, ethnobotanical surveys and laboratory investigation established identified natural plants species in the development of drug discovery to control the dengue fever.
引用
收藏
页码:1782 / 1816
页数:35
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