Measurement Of Cross Sections For The 232Th (P, 4n) 229Pa Reaction At Low Proton Energies

被引:25
|
作者
Jost, C. U. [1 ]
Griswold, J. R. [2 ,3 ]
Bruffey, S. H. [3 ]
Mirzadeh, S. [3 ]
Stracener, D. W. [4 ]
Williams, C. L. [5 ]
机构
[1] Univ Tennessee, Dept Phys & Astron, Knoxville, TN 37996 USA
[2] Univ Tennessee, Dept Nuclear Engn, Knoxville, TN 37996 USA
[3] Oak Ridge Natl Lab, Fuel Cycle & Isotope Div, Oak Ridge, TN 37831 USA
[4] Oak Ridge Natl Lab, Div Phys, Oak Ridge, TN 37831 USA
[5] Oak Ridge Associated Univ, Oak Ridge, TN 37831 USA
关键词
Medical isotopes; Thorium; accelerator; HRIBF; CU;
D O I
10.1063/1.4802383
中图分类号
O59 [应用物理学];
学科分类号
摘要
The alpha-emitters Ac-225 and Bi-213 are of great interest for alpha-radioimmunotherapy which uses radioisotopes attached to cancer-seeking antibodies to efficiently treat various types of cancers. Both radioisotopes are daughters of the long-lived Th-229 (t(1/2) = 7880y). Th-229 can be produced by proton irradiation of Th-232 and Th-230, either directly or through production of isobars that beta-decay into Th-229. To obtain excitation functions, Th-232 and Th-230 have been irradiated at the On-Line Test Facility at the Holifield Radioactive Ion Beam Facility at ORNL. Benchmark tests conducted with Cu and Ni foils show very good agreement with literature results. The experiments with thorium targets were focused on the production of Pa-229 and its daughter Ac-225 from both Th-232 and Th-230. Differential cross-sections for production of Pa-229 and other Pa isotopes have been obtained.
引用
收藏
页码:520 / 524
页数:5
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