Studies on the influence of combined administration of ochratoxin A, fumonisin B1, deoxynivalenol and T2 toxin on immune and defence reactions in weaner pigs

被引:18
|
作者
Müller, G [1 ]
Kielstein, P [1 ]
Rosner, H [1 ]
Berndt, A [1 ]
Heller, M [1 ]
Köhler, H [1 ]
机构
[1] BgVV Fachbereich 4, Fed Inst Hlth Protect Consumers & Vet Med, D-07743 Jena, Germany
关键词
mycotoxins; ochratoxin A; fumonisin; deoxynivalenol; T2; toxin; animal model; immunomodulation; microbial defence; weaner pig;
D O I
10.1046/j.1439-0507.1999.00503.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
In weaners, combined administration of fumonisin, deoxynivalenol and T2 together with ochratoxin A in quantities expected to be present in feeds of central European origin resulted, as a rule, in changes identical to those observed after single administration of ochratoxin A. Such reactions were partly compensated. Synergistic amplification of immunosuppressive changes due to the simultaneous intake of these mycotoxins in low concentrations is not to be expected.
引用
收藏
页码:485 / 493
页数:9
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