Risk Factors of Breast Cancer: A Systematic Review and Meta-Analysis

被引：105

作者：

Anothaisintawee, Thunyarat ^{[1
]}

Wiratkapun, Cholatip ^{[1
]}

Lerdsitthichai, Panuwat ^{[1
]}

Kasamesup, Vijj ^{[1
]}

Wongwaisayawan, Sansanee ^{[1
]}

Srinakarin, Jiraporn ^{[2
]}

Hirunpat, Siriporn ^{[3
]}

Woodtichartpreecha, Piyanoot ^{[3
]}

Boonlikit, Sarawan ^{[4
]}

Teerawattananon, Yot ^{[5
]}

Thakkinstian, Ammarin ^{[1
]}

机构：

[1] Mahidol Univ, Ramathibodi Hosp, Bangkok 10400, Thailand

[2] Khon Kaen Univ, Srinagarind Hosp, Khon Kaen, Thailand

[3] Prince Songkla Univ, Hat Yai, Thailand

[4] Natl Canc Inst, Bangkok, Thailand

[5] Minist Publ Hlth, Nonthaburi, Thailand

来源：

ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH | 2013年 / 25卷 / 05期

关键词：

breast cancer; meta-analysis; risk factor; systematic review; HORMONE-REPLACEMENT THERAPY; ORAL-CONTRACEPTIVE USE; ESTROGEN PLUS PROGESTIN; CARCINOMA IN-SITU; POPULATION-BASED COHORT; HISPANIC WHITE WOMEN; BODY-MASS INDEX; POSTMENOPAUSAL WOMEN; REPRODUCTIVE FACTORS; DIABETES-MELLITUS;

D O I：

10.1177/1010539513488795

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The etiology of breast cancer might be explained by 2 mechanisms, namely, differentiation and proliferation of breast epithelial cells mediated by hormonal factors. We performed a systematic review and meta-analysis to update effects of risk factors for both mechanisms. MEDLINE and EMBASE were searched up to January 2011. Studies that assessed association between oral contraceptives (OC), hormonal replacement therapy (HRT), diabetes mellitus (DM), or breastfeeding and breast cancer were eligible. Relative risks with their confidence intervals (CIs) were extracted. A random-effects method was applied for pooling the effect size. The pooled odds ratios of OC, HRT, and DM were 1.10 (95% CI = 1.03-1.18), 1.23 (95% CI = 1.21-1.25), and 1.14 (95% CI = 1.09-1.19), respectively, whereas the pooled odds ratio of ever-breastfeeding was 0.72 (95% CI = 0.58-0.89). Our study suggests that OC, HRT, and DM might increase risks, whereas breastfeeding might lower risks of breast cancer.

引用

页码：368 / 387

页数：20

共 50 条

[1] Breast cancer risk factors in Iran: a systematic review & meta-analysis
Shamshirian, Amir
Heydari, Keyvan
Shams, Zahra
Aref, Amir Reza
Shamshirian, Danial
Tamtaji, Omid Reza
Asemi, Zatollah
Shojaie, Layla
Mirzaei, Hamed
Mohammadi, Neda
Zibaee, Behdad
Karimifar, Keyvan
Zarandi, Bahman
Hedayatizadeh-Omran, Akbar
Alizadeh-Navaei, Reza
[J]. HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION, 2020, 41 (04)
[2] Breast cancer risk factors in Iran: A systematic review & meta-analysis
Shamshirian, A.
Heydari, K.
Shams, Z.
Aref, A. R.
Shamshirian, D.
Tamtaji, O. R.
Asemi, Z.
Mirzaei, H.
Mohammadi, N.
Zibaee, B.
Karimifar, K.
Zarandi, B.
Hedayatizadeh-Omran, A.
Alizadeh-Navaei, R.
[J]. ANNALS OF ONCOLOGY, 2020, 31 : S318 - S318
[3] Risk factors of pain in breast cancer survivors: a systematic review and meta-analysis
Laurence Leysen
David Beckwée
Jo Nijs
Roselien Pas
Thomas Bilterys
Sofie Vermeir
Nele Adriaenssens
[J]. Supportive Care in Cancer, 2017, 25 : 3607 - 3643
[4] Mammographic density and breast cancer risk factors: Systematic review and meta-analysis
Thakrar, Dixa
Grenville, Zoe
Desai, Trishna
Gathani, Toral
Reeves, Gillian K.
Barnes, Isobel
[J]. BREAST CANCER RESEARCH, 2023, 25
[5] Risk factors of pain in breast cancer survivors: a systematic review and meta-analysis
Leysen, Laurence
Beckwee, David
Nijs, Jo
Pas, Roselien
Bilterys, Thomas
Vermeir, Sofie
Adriaenssens, Nele
[J]. SUPPORTIVE CARE IN CANCER, 2017, 25 (12) : 3607 - 3643
[6] Risk factors for metachronous contralateral breast cancer: A systematic review and meta-analysis
Akdeniz, Delal
Schmidt, Marjanka K.
Seynaeve, Caroline M.
McCool, Danielle
Giardiello, Daniele
van den Broek, Alexandra J.
Hauptmann, Michael
Steyerberg, Ewout W.
Hooning, Maartje J.
[J]. BREAST, 2019, 44 : 1 - 14
[7] Analysis of risk factors associated with breast cancer in women: a systematic review and meta-analysis
Liu, Hulin
Shi, Suling
Gao, Jinnan
Guo, Jun
Li, Min
Wang, Linying
[J]. TRANSLATIONAL CANCER RESEARCH, 2022, 11 (05) : 1344 - 1353
[8] Intrauterine factors and risk of breast cancer: A systematic review and meta-analysis of current evidence
Xue, Fei
Michels, Karin B.
[J]. LANCET ONCOLOGY, 2007, 8 (12): : 1088 - 1100
[9] Risk Factors of Breast Cancer in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis
Namiranian, Nasim
Moradi-Lakeh, Maziar
Razavi-Ratki, Seid Kazem
Doayie, Mahdyie
Nojomi, Marzieh
[J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (21) : 9535 - 9541
[10] Migraine and Risk of Breast Cancer: A Systematic Review and Meta-analysis
Peng, Cheng
Wu, Kongyuan
Chen, Xiwen
Lang, Hui
Li, Changling
He, Li
Chen, Ning
[J]. CLINICAL BREAST CANCER, 2023, 23 (03) : E122 - E130

← 1 2 3 4 5 →