Medicinal chemistry of small and large molecules: Discovery of telcagepant and development of siRNA therapeutics

被引:0
|
作者
Shaw, Anthony [1 ]
机构
[1] Merck Res Labs, Dept RNAi Med Chem, West Point, PA 19486 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
699-ORGN
引用
收藏
页数:1
相关论文
共 50 条
  • [1] siRNA Based Approaches in Medicinal Chemistry and Drug Discovery
    Schiffelers, Raymond M.
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2012, 12 (02) : 67 - 68
  • [2] Small molecules as activators in medicinal chemistry (2000-2016)
    Hameed, Abdul
    Al-Rashida, Mariya
    Alharthy, Rima D.
    Uroos, Maliha
    Mughal, Ehsan Ullah
    Ali, Syed Abid
    Khan, Khalid Mohammed
    [J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 27 (10) : 1089 - 1110
  • [3] Quantum chemistry: Large molecules - Small computers
    Ahlrichs, R
    Elliott, SD
    Huniar, U
    [J]. BERICHTE DER BUNSEN-GESELLSCHAFT-PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 1998, 102 (06): : 795 - 804
  • [4] Current Small Molecule-Based Medicinal Chemistry Approaches for Neurodegeneration Therapeutics
    Sanghai, Nitesh
    Vuong, Billy
    Berk, Ahmet Burak
    Afridi, Muhammad Shaharyar K.
    Tranmer, Geoffrey K.
    [J]. CHEMMEDCHEM, 2024, 19 (09)
  • [5] THE DISCOVERY OF CAPTOPRIL - FROM LARGE ANIMALS TO SMALL MOLECULES
    OPIE, LH
    KOWOLIK, H
    [J]. CARDIOVASCULAR RESEARCH, 1995, 30 (01) : 18 - 25
  • [6] Functional Peptides and Small Molecules in Medicinal Chemistry-Part II
    Shen, Guohua
    Li, Yiwen
    Zhao, Linjie
    Wu, Haoxing
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 19 (03) : 186 - 186
  • [7] Advances and applications of supercritical fluid chromatography for small molecules medicinal chemistry
    Rosse, Gerard
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [8] Functional Peptides and Small Molecules in Medicinal Chemistry-Part I
    Shen, Guohua
    Lie, Yiwen
    Zhao, Linjie
    Wu, Haoxing
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 19 (01) : 2 - 3
  • [9] Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
    Kirk, Kenneth L.
    [J]. JOURNAL OF FLUORINE CHEMISTRY, 2006, 127 (08) : 1013 - 1029
  • [10] Combining genomics and metabolomics approaches to aid discovery and production of small molecules as therapeutics
    Prasanna, S. S.
    Reuben, S.
    Prasad, S. B. Benaka
    Rangappa, K. S.
    Swarup, S.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238