A novel C29 sterol from Clerodendrum cyrtophyllum

被引：4
|
作者：
Wang, Peng [1 ]
Guo, Fujiang [1 ]
Tan, Junjie [2 ]
Huang, Cheng [1 ]
Wang, Guangyin [1 ]
Li, Yiming [1 ]
机构：
[1] Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 04期
基金：
中国国家自然科学基金;
关键词：
sterols; Clerodendrum cyrtophyllum; anticancer; GLUCOSIDES;
D O I：
10.1007/s10600-012-0320-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A novel C29 sterol, stigmasta-5, 22, 25-trien-7-on-3 beta-ol, has been isolated from the branches of Clerodendrum cyrtophyllum with four other known sterols. Their structures were elucidated by means of spectroscopic studies, including H-1, C-13 NMR, and HR-ESI-MS. Bioassay tests show that they can inhibit Mcf-7 human breast cancer cell growth.
引用
收藏
页码：594 / 596
页数：3
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