Targeting metabolic vulnerabilities of MDSCs to enhance the antitumor activity of PD-1 blockade

被引：0
|
作者：
Kim, Sun Hye [1 ]
Li, Man [1 ]
Trousil, Sebastian [1 ]
Zheng, Bin [1 ]
机构：
[1] Massachusetts Gen Hosp, Charlestown, MA USA
来源：
CANCER IMMUNOLOGY RESEARCH | 2018年 / 6卷 / 09期
关键词：
D O I：
10.1158/2326-6074.TUMIMM17-A68
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A68
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Targeting metabolic vulnerabilities of MDSCs to enhance the anti-tumor activity of PD-1 blockade in melanoma
    Zheng, B.
    Kim, S.
    Li, M.
    Trousil, S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : S137 - S137
  • [2] Preclinical Data Supporting Antitumor Activity of PD-1 Blockade
    Curran, Michael A.
    CANCER JOURNAL, 2018, 24 (01): : 2 - 6
  • [3] Metabolically reprogram MDSCs by targeting Pim kinases to overcome resistance to PD-1 blockade immunotherapy
    Chen, Yao
    Topchyan, Paytsar
    Jiang, Aimin
    Chen, Yiliang
    Silverstein, Roy
    Cui, Weiguo
    Xin, Gang
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [4] COMBINATION OF VEGF-A AND PD-1 BLOCKADE MAY ENHANCE ANTITUMOR EFFICACY IN GBM
    Long, Yu
    Yang, Changlin
    Jin, Linchun
    Ge, Haitao
    Bao, Hongbo
    Flores, Catherine
    Lin, Zhiguo
    Mitchell, Duane
    Huang, Jianping
    NEURO-ONCOLOGY, 2016, 18 : 91 - 91
  • [5] The enhanced antitumor activity of bispecific antibody targeting PD-1/PD-L1 signaling
    Tianye Li
    Mengke Niu
    Jianwei Zhou
    Kongming Wu
    Ming Yi
    Cell Communication and Signaling, 22
  • [6] The enhanced antitumor activity of bispecific antibody targeting PD-1/PD-L1 signaling
    Li, Tianye
    Niu, Mengke
    Zhou, Jianwei
    Wu, Kongming
    Yi, Ming
    CELL COMMUNICATION AND SIGNALING, 2024, 22 (01)
  • [7] Nivolumab: targeting PD-1 to bolster antitumor immunity
    Brahmer, Julie R.
    Hammers, Hans
    Lipson, Evan J.
    FUTURE ONCOLOGY, 2015, 11 (09) : 1307 - 1326
  • [8] PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model
    Yuan Li
    Yang Du
    Ting Sun
    Huadan Xue
    Zhengyu Jin
    Jie Tian
    BMC Cancer, 18
  • [9] PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model
    Li, Yuan
    Du, Yang
    Sun, Ting
    Xue, Huadan
    Jin, Zhengyu
    Tian, Jie
    BMC CANCER, 2018, 18
  • [10] PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model
    Li, Yuan
    Du, Yang
    Sun, Ting
    Xue, Huadan
    Tian, Jie
    Jin, Zhengyu
    CANCER RESEARCH, 2017, 77
12345