A phase I study of oral panobinostat (LBH589) alone and in combination with docetaxel (Doc) and prednisone in castration-resistant prostate cancer (CRPC)

被引:3
|
作者
Rathkopf, D. E.
Wong, B. Y.
Ross, R. W.
George, D. J.
Picus, J.
Tanaka, E.
Chen, Y.
Atadja, P.
Yang, W.
Culver, K. W.
Scher, H. I.
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Nevada Canc Inst, Las Vegas, NV USA
[3] Dana Farber Canc Inst, Boston, MA 02115 USA
[4] Duke Univ, Med Ctr, Durham, NC USA
[5] Washington Univ, St Louis, MO USA
[6] Novartis Inst Biomed Res, Cambridge, MA USA
关键词
D O I
10.1200/jco.2008.26.15_suppl.5152
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5152
引用
收藏
页数:1
相关论文
共 50 条
  • [1] A PHASE I STUDY OF ORAL PANOBINOSTAT (LBH589) ALONE AND IN COMBINATION WITH DOCETAXEL (DOC) AND PREDNISONE IN CASTRATION-RESISTANT PROSTATE CANCER (CRPC)
    Rathkopf, D. E.
    Wong, B. Y.
    Ross, R. W.
    George, D. J.
    Picus, J.
    Atadja, P.
    Yang, W.
    Culver, K. W.
    Woo, M. M.
    Scher, H. I.
    ANNALS OF ONCOLOGY, 2008, 19 : 199 - 200
  • [2] A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer
    Dana Rathkopf
    Bryan Y. Wong
    Robert W. Ross
    Aseem Anand
    Erika Tanaka
    Margaret M. Woo
    Jing Hu
    Andy Dzik-Jurasz
    Wei Yang
    Howard I. Scher
    Cancer Chemotherapy and Pharmacology, 2010, 66 : 181 - 189
  • [3] A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer
    Rathkopf, Dana
    Wong, Bryan Y.
    Ross, Robert W.
    Anand, Aseem
    Tanaka, Erika
    Woo, Margaret M.
    Hu, Jing
    Dzik-Jurasz, Andy
    Yang, Wei
    Scher, Howard I.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2010, 66 (01) : 181 - 189
  • [4] A phase I study of oral panobinostat (LBH589) in Japanese patients with advanced solid tumors
    Fukutomi, Akira
    Hatake, Kiyohiko
    Matsui, Kaoru
    Sakajiri, Sakura
    Hirashima, Tomonori
    Tanii, Hiromi
    Kobayashi, Ken
    Yamamoto, Nobuyuki
    INVESTIGATIONAL NEW DRUGS, 2012, 30 (03) : 1096 - 1106
  • [5] A phase I study of oral panobinostat (LBH589) in Japanese patients with advanced solid tumors
    Akira Fukutomi
    Kiyohiko Hatake
    Kaoru Matsui
    Sakura Sakajiri
    Tomonori Hirashima
    Hiromi Tanii
    Ken Kobayashi
    Nobuyuki Yamamoto
    Investigational New Drugs, 2012, 30 : 1096 - 1106
  • [6] A phase I study of oral panobinostat (LBH589) in Japanese patients with advanced solid tumours
    Okamoto, N.
    Hatake, K.
    Yamamoto, N.
    Takahashi, S.
    Boku, N.
    Kobayashi, K.
    Sakatani, K.
    Hirashima, T.
    Matsui, K.
    EJC SUPPLEMENTS, 2008, 6 (12): : 133 - 133
  • [7] Phase Ib dose finding trial of intravenous panobinostat with docetaxel in patients with castration-resistant prostate cancer (CRPC)
    Rathkopf, D. E.
    Chi, K. N.
    Vaishampayan, U.
    Hotte, S.
    Vogelzang, N.
    Alumkal, J.
    Agrawal, M.
    Nydam, T. M.
    Fandi, A.
    Scher, H. I.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
  • [8] Overcoming docetaxel resistance in advanced castration-resistant prostate cancer (CRPC): A phase I/II trial of the combination of temsirolimus and docetaxel
    Duran, Ignacio
    Montagut, Clara
    Calvo, Emiliano
    Galtes, Susana
    Navarrete, Alicia
    Rodriguez-Pascual, Jesus
    Hidalgo, Manuel
    Francisco Rodriguez-Moreno, Juan
    Cubillo, Antonio
    Garcia, Antonia
    Sanchez, Lorena
    Barbas, Coral
    Viqueira, Andrea
    Bellmunt, Joaquim
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (05)
  • [9] Phase I study of panobinostat (LBH589) and letrozole in postmenopausal women with metastatic breast cancer
    Tan, Winston
    Allred, Jacob B.
    Moreno-Aspitia, Alvaro
    Northfelt, Donald W.
    Ingle, James N.
    Perez, Edith A.
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [10] Phase I Study of Panobinostat (LBH589) and Letrozole in Postmenopausal Metastatic Breast Cancer Patients
    Tan, Winston W.
    Allred, Jacob B.
    Moreno-Aspitia, Alvaro
    Northfelt, Donald W.
    Ingle, James N.
    Goetz, Matthew P.
    Perez, Edith A.
    CLINICAL BREAST CANCER, 2016, 16 (02) : 82 - 86