Metabolic engineering of plants for polyunsaturated fatty acid production

被引：22
|
作者：
Truksa, Martin [2 ]
Vrinten, Patricia [2 ]
Qiu, Xiao [1 ]
机构：
[1] Univ Saskatchewan, Dept Food & Bioprod Sci, Saskatoon, SK, Canada
[2] Bioriginal Food & Sci Corp, Saskatoon, SK, Canada
来源：
MOLECULAR BREEDING | 2009年 / 23卷 / 01期
关键词：
Polyunsaturated fatty acids; Transgenic plants; Metabolic engineering; GAMMA-LINOLENIC ACID; EICOSAPENTAENOIC ACID; DOCOSAHEXAENOIC ACID; SACCHAROMYCES-CEREVISIAE; HETEROLOGOUS EXPRESSION; DELTA-6; DESATURASE; BIOSYNTHESIS; DELTA(6)-DESATURASE; IDENTIFICATION; GENE;
D O I：
10.1007/s11032-008-9218-y
中图分类号：
S3 [农学（农艺学）];
学科分类号：
0901 ;
摘要：
Very-long-chain polyunsaturated fatty acids (VLCPUFAs) have demonstrated health benefits. Currently, the main sources for these fatty acids are oils from fish and microbes. However, shrinking fish populations and the high cost of microbial oil extraction are making the economic sustainability of these sources questionable. Metabolic engineering of oilseed crops could provide a novel and sustainable source of VLCPUFAs. Recently, genes encoding desaturases and elongases from microbes have been identified and successfully expressed in oilseed plants. However, the levels of VLCPUFAs produced in transgenic plants expressing these genes are still much lower than those found in native microbes. This review assesses the recent progress and future perspectives in the metabolic engineering of PUFAs in plants.
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页码：1 / 11
页数：11
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