Ionic Liquid Surfactant. mediated Ultrasonic. assisted Extraction Coupled with HPLC for the Determination of Five Rare Ginsenosides in Panax notoginseng (Burk.) F. H. Chen

被引：7
|
作者：
Li Lanjie [1 ]
Li Xuwen [1 ]
Ding Jian [2 ]
Liu Ying [1 ]
Wu Qian [1 ]
Wang Xiaozhong [1 ]
Li Min [1 ]
Jin Yongri [1 ]
机构：
[1] Jilin Univ, Coll Chem, Changchun 130012, Peoples R China
[2] Jilin Univ, Hosp 4, Changchun 130013, Peoples R China
来源：
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2016年 / 37卷 / 03期
关键词：
Ionic liquid; Ultrasonic. assisted extraction; Panax notoginseng (Burk.) F. H. Chen; Rare ginsenoside; SAPONINS; RG(3);
D O I：
10.7503/cjcu20150703
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method of ultrasonic. assisted ionic liquid. salt aqueous two. phase extraction coupled with high. performance liquid chromatography(HPLC) was developed for the determination of the contents of five rare ginsenosides[20(S)-Rg(2), 20(S)-Rh-1, Rk(3), 20(S)-Rg(3) and Rk(1)] in Panax notoginseng(Burk.) F. H. Chen(Sanqi). The factors influencing the ultrasonic. assisted extraction were investigated in detail. Under the optimized conditions, satisfactory extraction efficiency was achieved with the recoveries ranging from 92. 07% to 110. 55%, and the RSDs were lower than 5. 43%. The results showed that the method had the advantages of fast, efficient, accurate and environmental protection. It provided a strong basis for the extraction, enrich. ment and analysis of the trace bio-active chemical composition of the traditional Chinese medicine and its preparations.
引用
收藏
页码：454 / 459
页数：6
相关论文
共 18 条
  • [1] [Anonymous], PXIE6672 NI CORP
  • [2] Ionic liquid-based ultrasonic-assisted extraction of piperine from white pepper
    Cao, Xiaoji
    Ye, Xuemin
    Lu, Yanbin
    Yu, Yi
    Mo, Weimin
    [J]. ANALYTICA CHIMICA ACTA, 2009, 640 (1-2) : 47 - 51
  • [3] Ionic Liquid-based Microwave-assisted Liquid-liquid Microextraction and High Performance Liquid Chromatography Determination of Sulfonamides from Animal Oils
    Feng Xu-dong
    Liang Fang-hui
    Su Rui
    Wu Li-jie
    Li Xue-yuan
    Wang Xing-hua
    Zhang Han-qi
    Yu Ai-min
    [J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2013, 29 (04) : 647 - 652
  • [4] A rapid method for the simultaneous determination of 11 saponins in Panax notoginseng using ultra performance liquid chromatography
    Guan, J.
    Lai, C. M.
    Li, S. P.
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 44 (04) : 996 - 1000
  • [5] HwangI G., 2010, FOOD SCI BIOTECHNOL, V19, P941
  • [6] ESR study on the structure and hydroxyl radical-scavenging activity relationships of ginsenosides isolated from Panax ginseng C. A.!MEYER
    Kang, Ki Sung
    Yokozawa, Takako
    Yamabe, Noriko
    Kim, Hyun Young
    Park, Jeong Hill
    [J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2007, 30 (05) : 917 - 921
  • [7] Stereospecificity in hydroxyl radical scavenging activities of four ginsenosides produced by heat processing
    Kang, Ki Sung
    Kim, Hyun Young
    Yamabe, Noriko
    Yokozawa, Takako
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (19) : 5028 - 5031
  • [8] Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells
    Kim, HS
    Lee, EH
    Ko, SR
    Choi, KJ
    Park, JH
    Im, DS
    [J]. ARCHIVES OF PHARMACAL RESEARCH, 2004, 27 (04) : 429 - 435
  • [9] Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
    Kim, Young-Joo
    Kwon, Hak Cheol
    Ko, Hyeonseok
    Park, Jeong Hill
    Kim, Hyun Young
    Yoo, Ji-Hye
    Yang, Hyun Ok
    [J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2008, 31 (05) : 826 - 830
  • [10] Liu H Z, 1982, Yao Xue Xue Bao, V17, P801
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