Current and Emerging Therapies for Alzheimer's Disease

被引：24
|
作者：
Nygaard, Haakon B. [1 ]
机构：
[1] Yale Univ, Sch Med, Dept Neurol, New Haven, CT 06511 USA
来源：
CLINICAL THERAPEUTICS | 2013年 / 35卷 / 10期
基金：
美国国家卫生研究院;
关键词：
MILD COGNITIVE IMPAIRMENT; CHRONIC DIVALPROEX SODIUM; DOUBLE-BLIND; INTRAVENOUS IMMUNOGLOBULIN; SYNAPTIC PLASTICITY; CEREBROSPINAL-FLUID; DONEPEZIL; EFFICACY; RIVASTIGMINE; SAFETY;
D O I：
10.1016/j.clinthera.2013.09.009
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly increasing worldwide prevalence. Although no cure for AD has yet been found, substantial progress has been made in our understanding of AD pathogenesis. This progress has led to the development of numerous promising compounds in various stages of clinical testing. In this review, the current pharmacologic treatments for AD are discussed in detail, followed by an overview of the main experimental strategies that will shape AD therapeutics over the next decade. (C) 2013 Elsevier HS Journals, Inc. All rights reserved,
引用
收藏
页码：1480 / 1489
页数：10
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