Pneumococcal pneumonia vaccine breakthroughs and failures after 13-valent pneumococcal conjugated vaccine

被引：8

作者：

Almeida, Ana Filipe ^{[1
]}

Sobrinho-Simoes, Joana ^{[2
]}

Ferraz, Catarina ^{[3
]}

Nunes, Teresa ^{[3
]}

Vaz, Luisa ^{[3
]}

机构：

[1] Sao Joao Hosp, Dept Paediat, Oporto, Portugal

[2] Sao Joao Hosp, Dept Clin Microbiol Lab, Oporto, Portugal

[3] Sao Joao Hosp, Dept Paediat Pulmonol, Oporto, Portugal

来源：

EUROPEAN JOURNAL OF PUBLIC HEALTH | 2016年 / 26卷 / 05期

关键词：

CHILDREN; DISEASE;

D O I：

10.1093/eurpub/ckw089

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The rate of invasive pneumococcal disease has markedly declined after the introduction of pneumococcal conjugated vaccines. In spite of the high effectiveness of this vaccine, there are some reports of vaccine failure and vaccine breakthroughs. Data on children with pneumococcal pneumonia in a European tertiary Hospital, from 2012 to 2014, were retrospectively collected before the implementation of pneumococcal conjugated vaccines in our country. We found four cases of pneumococcal serotype 3 vaccine failure and three cases of vaccine breakthroughs (two with serotype 3 and one with serotype 19A). All of these children were previously healthy.

引用

页码：887 / 889

页数：3

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