Topiramate Treatment of Alcohol Use Disorder in Clinical Practice

被引：4

作者：

Jefee-Bahloul, Hussam ^{[1
,3
]}

Jorandby, Lantie ^{[2
]}

Arias, Albert J. ^{[3
]}

机构：

[1] Univ Massachusetts, Med Sch, Worcester, MA 01605 USA

[2] Massachusetts Gen Hosp, Boston, MA 02114 USA

[3] Yale Univ, Sch Med, New Haven, CT USA

来源：

JOURNAL OF ADDICTION MEDICINE | 2019年 / 13卷 / 01期

关键词：

alcohol dependence; alcohol use disorder; alcoholism; anticonvulsant; medication treatment; topiramate; POSTTRAUMATIC-STRESS-DISORDER; DEPENDENCE; COCAINE; METAANALYSIS; INDIVIDUALS; TRIAL;

D O I：

10.1097/ADM.0000000000000444

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Topiramate is an anticonvulsant medication with increasingly strong evidence, supporting its use for treating alcohol use disorder (AUD) based on clinical trials. These clinical cases summarize the initiation and titration of topiramate in AUD treatment. The core issues of patient selection, consideration of comorbid psychiatric and medical conditions, side-effect profile, safety and effectiveness are reviewed. Addiction physicians should take a leading role in using topiramate to treat AUDs, working with patients to balance the benefits of topiramate with the risk.

引用

页码：23 / 27

页数：5

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