Assessment of prescribing pattern of drugs and completeness of prescriptions as per the World Health Organization prescribing indicators in various Indian tertiary care centers: A multicentric study by Rational Use of Medicines Centers-Indian Council of Medical Research network under National Virtual Centre Clinical Pharmacology activity

被引：2

作者：

Joshi, R. ^{[1
]}

Medhi, B. ^{[1
]}

Prakash, A. ^{[1
]}

Chandy, S. ^{[2
]}

Ranjalkar, J. ^{[2
]}

Bright, H. ^{[2
]}

Basker, J. ^{[2
]}

Govindraj, L. ^{[2
]}

Chugh, P. ^{[3
]}

Tripathi, C. ^{[3
]}

Badyal, D. ^{[4
]}

Balakrishnan, S. ^{[5
]}

Jhaj, R. ^{[5
]}

Shukla, A. ^{[5
]}

Atal, S. ^{[5
]}

Najmi, A. ^{[5
]}

Banerjee, A. ^{[5
]}

Kamat, S. ^{[6
]}

Tripathi, R. ^{[6
]}

Shetty, Y. ^{[6
]}

Parmar, U. ^{[6
]}

Rege, N. ^{[6
]}

Dikshit, H. ^{[7
]}

Mishra, H. ^{[7
]}

Roy, S. ^{[7
]}

Chatterjee, S. ^{[8
]}

Hazra, A. ^{[8
]}

Bhattacharya, M. ^{[8
]}

Das, D. ^{[8
]}

Trivedi, N. ^{[9
]}

Shah, P. ^{[9
]}

Chauhan, J. ^{[9
]}

Desai, C. ^{[10
]}

Gandhi, A. ^{[10
]}

Patel, P. ^{[10
]}

Shah, S. ^{[10
]}

Sheth, S. ^{[10
]}

Raveendran, R. ^{[11
]}

Mathaiyan, J. ^{[11
]}

Manikandan, S. ^{[11
]}

Jeevitha, G. ^{[11
]}

Gupta, P. ^{[12
]}

Sarangi, S. ^{[12
]}

Yadav, H. ^{[12
]}

Singh, S. ^{[12
]}

Kaushal, S. ^{[13
]}

Arora, S. ^{[13
]}

Gupta, K. ^{[13
]}

Jain, S. ^{[13
]}

Cherian, J. ^{[14
]}

机构：

[1] Post Grad Inst Med Educ & Res, Dept Pharmacol, Chandigarh, India

[2] Christian Med Coll & Hosp, Dept Pharmacol & Clin Pharmacol, Vellore, Tamil Nadu, India

[3] Vardhman Mahavir Med Coll, New Delhi, India

[4] Christian Med Coll & Hosp, Dept Pharmacol, Ludhiana, Punjab, India

[5] All India Inst Med Sci, Dept Pharmacol, Bhopal, India

[6] Seth GS Med Coll & KEM Hosp, Dept Pharmacol & Therapeut, Mumbai, Maharashtra, India

[7] Indira Gandhi Inst Med Sci, Dept Pharmacol, Patna, Bihar, India

[8] Inst Post Grad Med Educ & Res, Dept Pharmacol, Kolkata, West Bengal, India

[9] Govt Med Coll, Dept Pharmacol, Baroda, Gujarat, India

[10] BJ Med Coll, Dept Pharmacol, Ahmadabad, Gujarat, India

[11] Jawaharlal Inst Post Med Educ & Res, Dept Pharmacol, Pondicherry, India

[12] All India Inst Med Sci, Dept Pharmacol, New Delhi, India

[13] Dayanand Med Coll & Hosp, Dept Pharmacol, Ludhiana, Punjab, India

[14] Indian Council Med Res, New Delhi, India

来源：

INDIAN JOURNAL OF PHARMACOLOGY | 2022年 / 54卷 / 05期

关键词：

Appropriateness; fixed-dose combination; national list of essential medicines; prescription audit; rational use of drugs; DIETARY-SUPPLEMENTS; COST-ANALYSIS; HOSPITALS; ADULTS;

D O I：

10.4103/ijp.ijp_976_21

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

OBJECTIVE: The rational use of medicines as per the World Health Organization (WHO) should be practiced globally. However, data regarding the completeness of the prescriptions and their rational use is lacking from developing countries like India. Thus, the aim of this study was to assess the prescribing patterns of drugs and completeness of prescriptions as per WHO core drug use and complementary indicators to provide real-life examples for the Indian Council of Medical Research (ICMR) online prescribing skill course for medical graduates. METHODS: Prescriptions of the patients, fulfilling inclusion criteria, attending Outpatient Departments of various specialties of tertiary care hospitals, were collected by thirteen ICMR Rational use of medicines centers located in tertiary care hospitals, throughout India. Prescriptions were evaluated for rational use of medicines according to the WHO guidelines and for appropriateness as per standard treatment guidelines using a common protocol approved by local Ethics committees. RESULTS: Among 4838 prescriptions, an average of about three drugs (3.34) was prescribed to the patients per prescription. Polypharmacy was noted in 83.05% of prescriptions. Generic drugs were prescribed in 47.58% of the prescriptions. Further, antimicrobials were prescribed in 17.63% of the prescriptions and only 4.98% of prescriptions were with injectables. During the prescription evaluation, 38.65% of the prescriptions were incomplete due to multiple omissions such as dose, duration, and formulation. CONCLUSION: Most of the parameters in the present study were out of the range of WHO-recommended prescribing indicators. Therefore, effective intervention program, like training, for the promotion of rational drug use practice was recommended to improve the prescribing pattern of drugs and the quality of prescriptions all over the country.

引用

页码：321 / 328

页数：8