Infectious diseases in the genomic era

被引:1
|
作者
Moreno Switt, Andrea I. [1 ]
Toledo, Viviana [1 ]
机构
[1] Univ Andres Bello, Escuela Med Vet, Fac Ecol & Recursos Nat, Santiago, Chile
来源
REVISTA CHILENA DE INFECTOLOGIA | 2015年 / 32卷 / 05期
关键词
Genomics; molecular epidemiology; next generation sequencing; OUTBREAK; BACTERIAL; LINEAGES; IDENTIFICATION; METAGENOMICS; SURVEILLANCE; TRANSMISSION; ENTERITIDIS; DISCOVERY; PROMISE;
D O I
10.4067/S0716-10182015000600013
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Next generation sequencing (NGS) technologies have arrived, changing research and infectious disease research into a new era, the "genomic era". Currently, the developed world is introducing NGS in a number of applications, including clinical diagnostics, epidemiology, and microbiology. In developing countries NGS is being progressively introduced. Technologies currently available allow to sequence the whole genome of bacterial and viral strains for an approximate cost of $100 USD, which is highly cost savings compared to old-technologies for genome sequencing. Here we review recent publication of whole genome sequencing used for, (i) tracking of foodborne outbreaks, with emphasis in Salmonella and Listeria monocytogenes, (ii) building genomic databases for Governments, (iii) investigating nosocomial infections, and (iv) clinical diagnosis. The genomic era is here to stay and researchers should use these "massive databases" generated by this technology to decrease infectious diseases and thus improve health of humans and animals.
引用
收藏
页码:571 / 576
页数:6
相关论文
共 50 条
  • [1] Infectious disease in the genomic era
    Yang, Xiaonan
    Yang, Hongliang
    Zhou, Gangqiao
    Zhao, Guo-Ping
    [J]. ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, 2008, 9 : 21 - 48
  • [2] Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era -: A Review
    Speranca, Marcia Aparecida
    Capurro, Margareth Lara
    [J]. MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2007, 102 (04): : 425 - 433
  • [3] Introduction: genomic approaches in infectious diseases
    Schnappinger, Dirk
    Ehrt, Sabine
    [J]. MICROBES AND INFECTION, 2006, 8 (06) : 1611 - 1612
  • [4] The Metamorphosis of Infectious Diseases in the Modern Era
    Chan, G. C. F.
    [J]. HONG KONG JOURNAL OF PAEDIATRICS, 2013, 18 (01) : 1 - 2
  • [5] Targeting infectious diseases in the genomics era
    Bagnoli, Fabio
    Rappuoli, Rino
    [J]. CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2006, 7 (08) : 695 - 698
  • [6] Sustainability in an era of emerging infectious diseases
    Carruthers, Jane
    [J]. SOUTH AFRICAN JOURNAL OF SCIENCE, 2020, 116 (3-4) : 1 - 1
  • [7] Prevention of chronic diseases in the genomic era
    Nagyova, I.
    [J]. EUROPEAN JOURNAL OF PUBLIC HEALTH, 2017, 27
  • [8] Global governmentality: Biosecurity in the era of infectious diseases
    Jappah, Jlateh Vincent
    Smith, Danielle Taana
    [J]. GLOBAL PUBLIC HEALTH, 2015, 10 (10) : 1139 - 1156
  • [9] Monitoring infectious diseases in the big data era
    Zou, Yuanqiang
    Peng, Yousong
    Deng, Lizong
    Jiang, Taijiao
    [J]. SCIENCE BULLETIN, 2015, 60 (01) : 144 - 145
  • [10] Infectious diseases: a call for manuscripts in an interdisciplinary era
    Stein, R. A.
    [J]. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2013, 67 (02) : 99 - 103