Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits

被引:789
|
作者
Shahidi, Fereidoon [1 ]
Ambigaipalan, Priyatharini [1 ]
机构
[1] Mem Univ Newfoundland, Dept Biochem, St John, NF A1B 3X9, Canada
关键词
omega-3; fish oil; health benefits; metabolism; bioavailability; cardiovascular disease; LONG-CHAIN OMEGA-3-FATTY-ACIDS; FISH-OIL SUPPLEMENTATION; CORONARY-HEART-DISEASE; PLACEBO-CONTROLLED TRIAL; ALPHA-LINOLENIC ACID; CONTROLLED CLINICAL-TRIAL; QUALITY-OF-LIFE; DOCOSAHEXAENOIC ACID; DOUBLE-BLIND; CARDIOVASCULAR-DISEASE;
D O I
10.1146/annurev-food-111317-095850
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Omega-3 polyunsaturated fatty acids (PUFAs) include a-linolenic acid (ALA; 18:3 omega-3), stearidonic acid (SDA; 18:4 omega-3), eicosapentaenoic acid (EPA; 20:5 omega-3), docosapentaenoic acid (DPA; 22:5 omega-3), and docosahexaenoic acid (DHA; 22:6 omega-3). In the past few decades, many epidemiological studies have been conducted on the myriad health benefits of omega-3 PUFAs. In this review, we summarized the structural features, properties, dietary sources, metabolism, and bioavailability of omega-3 PUFAs and their effects on cardiovascular disease, diabetes, cancer, Alzheimer's disease, dementia, depression, visual and neurological development, and maternal and child health. Even though many health benefits of omega-3 PUFAs have been reported in the literature, there are also some controversies about their efficacy and certain benefits to human health.
引用
收藏
页码:345 / 381
页数:37
相关论文
共 50 条
  • [1] The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence
    Ruxton, CHS
    Reed, SC
    Simpson, MJA
    Millington, KJ
    JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2004, 17 (05) : 449 - 459
  • [2] The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence
    Ruxton, C. H. S.
    Reed, S. C.
    Simpson, M. J. A.
    Millington, K. J.
    JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2007, 20 (03) : 275 - 285
  • [3] Omega-3 polyunsaturated fatty acids: Recent aspects in relation to health benefits
    Jahangiri, A
    Leifert, WR
    McMurchie, EJ
    FOOD AUSTRALIA, 2002, 54 (03): : 74 - 77
  • [4] Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport
    Gammone, Maria Alessandra
    Riccioni, Graziano
    Parrinello, Gaspare
    D'Orazio, Nicolantonio
    NUTRIENTS, 2019, 11 (01)
  • [5] Omega-3 polyunsaturated fatty acids and skeletal health
    Watkins, BA
    Li, Y
    Lippman, HE
    Seifert, MF
    EXPERIMENTAL BIOLOGY AND MEDICINE, 2001, 226 (06) : 485 - 497
  • [6] Metabolic Health Benefits of Long-Chain Omega-3 Polyunsaturated Fatty Acids
    Howe, Peter
    Buckley, Jon
    MILITARY MEDICINE, 2014, 179 (11) : 138 - 143
  • [7] Omega-3 polyunsaturated fatty acids
    Forse, RA
    Chavali, SR
    IMMUNE CONSEQUENCES OF TRAUMA, SHOCK AND SEPSIS - MECHANISMS AND THERAPEUTIC APPROACHES, VOL II, PTS 1 AND 2, 1996, : 906 - 911
  • [8] Omega-3 polyunsaturated fatty acids
    Hull, Mark A.
    BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2011, 25 (4-5) : 547 - 554
  • [9] Omega-3 polyunsaturated fatty acids
    Potherat, JJ
    OMEGA-3 LIPOPROTEINS AND ATHEROSCLEROSIS, 1996, : 7 - 22
  • [10] Omega-3 polyunsaturated fatty acids and human health outcomes
    Calder, Philip C.
    Yaqoob, Parveen
    BIOFACTORS, 2009, 35 (03) : 266 - 272