CD133 in the Selection of Epidermal Stem Cells in Mice: Steps in the Right Direction

被引：3
|
作者：
Nordvig, Anna S. [2 ]
Owens, David M. [2 ,3 ]
Morris, Rebecca J. [1 ]
机构：
[1] Univ Minnesota, Hormel Inst, Lab Stem Cells & Canc, Austin, MN 55912 USA
[2] Columbia Univ, Dept Dermatol, Coll Phys & Surg, New York, NY 10027 USA
[3] Columbia Univ, Coll Phys & Surg, Dept Pathol & Cell Biol, New York, NY USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2012年 / 132卷 / 11期
关键词：
KERATINOCYTES; CANCER;
D O I：
10.1038/jid.2012.322
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Charruyer and colleagues (this issue) report two significant advances to the field of cutaneous keratinocyte stem cells: a pair of new selectable markers that recognize a subset of alpha 6(+)CD34(+) label-retaining cells, and an in vivo limiting dilution assay for keratinocyte stem cells with long-term repopulating ability. This work has important implications for keratinocyte stem cell identification and assay, as well as for the identification of target cells in non-melanoma skin cancer.
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页码：2492 / 2494
页数：3
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