Alpinetin/hydroxypropyl-β-cyclodextrin host-guest system: Preparation, characterization, inclusion mode, solubilization and stability

被引：65
|
作者：
Ma, Shui-Xian [2 ,3 ]
Chen, Wen [1 ]
Yang, Xiao-Dong [1 ]
Zhang, Na [2 ]
Wang, Shao-Jie [2 ]
Liu, Lin [4 ]
Yang, Li-Juan [2 ,3 ]
机构：
[1] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China
[2] Yunnan Univ Nat, Key Lab Ethn Med Resource Chem State Ethn Affairs, Kunming 650500, Peoples R China
[3] Yunnan Univ Nat, Engn Lab Polylact Acid Based Funct Mat Yunnan, Kunming 650500, Peoples R China
[4] Yunnan Reascend Tobacco Technol Grp Co LTD, Kunming 650106, Peoples R China
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2012年 / 67-68卷
关键词：
Alpinetin; Hydroxypropyl-beta-cyclodextrin; Inclusion complex; Solubilization; Stability; BRIDGED BIS(BETA-CYCLODEXTRIN)S; BINDING; COMPLEXES; ALPINETIN; CARDAMONIN; CARRIERS;
D O I：
10.1016/j.jpba.2012.04.038
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The inclusion complexation behavior, characterization and binding ability of alpinetin with hydroxypropyl-beta-cyclodextrin (HP beta CD) has been investigated in both solution and the solid state by means of UV-vis spectroscopy, FT-IR, H-1 and 2D NMR, XRD, SEM and DSC. The results showed that the water solubility and stability of alpinetin were obviously increased in the inclusion complex with HP beta CD. This satisfactory water solubility and high stability of the alpinetin/HP beta CD complex will be potentially useful for its application as herbal medicine or healthcare products. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：193 / 200
页数：8
相关论文
共 50 条
  • [1] Crassicauline A/β-cyclodextrin host-guest system: Preparation, characterization, inclusion mode, solubilization and stability
    Chen, Wen
    Yang, Li-Juan
    Ma, Shui-Xian
    Yang, Xiao-Dong
    Fan, Bao-Min
    Lin, Jun
    CARBOHYDRATE POLYMERS, 2011, 84 (04) : 1321 - 1328
  • [2] Artemether/hydroxypropyl-β-cyclodextrin host-guest system: Characterization, phase-solubility and inclusion mode
    Yang, Bo
    Lin, Jun
    Chen, Yong
    Liu, Yu
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (17) : 6311 - 6317
  • [3] Host-guest system of hesperetin and β-cyclodextrin or its derivatives: Preparation, characterization, inclusion mode, solubilization and stability
    Yang, Li-Juan
    Xia, Sha
    Ma, Shui-Xian
    Zhou, Shu-Ya
    Zhao, Xue-Qiu
    Wang, Shu-Hui
    Li, Min-Yan
    Yang, Xiao-Dong
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 59 : 1016 - 1024
  • [4] Host-guest interaction between brazilin and hydroxypropyl-β-cyclodextrin: Preparation, inclusion mode, molecular modelling and characterization
    Yang, Li-Juan
    Chang, Qing
    Zhou, Shu-Ya
    Yang, Yun-Han
    Xia, Fu-Ting
    Chen, Wen
    Li, Minyan
    Yang, Xiao-Dong
    DYES AND PIGMENTS, 2018, 150 : 193 - 201
  • [5] Host-Guest System of Nimbin and β-Cyclodextrin or Its Derivatives: Preparation, Characterization, Inclusion Mode, and Solubilization
    Yang, Li-Juan
    Yang, Bo
    Chen, Wen
    Huang, Rong
    Yan, Sheng-Jiao
    Lin, Jun
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (15) : 8545 - 8552
  • [6] Host-guest system of taxifolin and native cyclodextrin or its derivative: Preparation, characterization, inclusion mode, and solubilization
    Yang, Li-Juan
    Chen, Wen
    Ma, Shui-Xian
    Gao, Yun-Tao
    Huang, Rong
    Yan, Sheng-Jiao
    Lin, Jun
    CARBOHYDRATE POLYMERS, 2011, 85 (03) : 629 - 637
  • [7] Host-guest inclusion complex of quercetin and hydroxypropyl-β-cyclodextrin A calorimetric study
    D'Aria, Federica
    Serri, Carla
    Niccoli, Marcella
    Mayol, Laura
    Quagliariello, Vincenzo
    Iaffaioli, Rosario Vincenzo
    Biondi, Marco
    Giancola, Concetta
    JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2017, 130 (01) : 451 - 456
  • [8] Preparation and characterization of host-guest system between inosine and β-cyclodextrin through inclusion mode
    Prabu, Samikannu
    Sivakumar, Krishnamurty
    Swaminathan, Meenakshisundaram
    Rajamohan, Rajaram
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2015, 147 : 151 - 157
  • [9] Study on a host-guest interaction of hydroxypropyl-β-cyclodextrin with ofloxacin
    Misiuk, Wieslawa
    Jozefowicz, Magdalena
    JOURNAL OF MOLECULAR LIQUIDS, 2015, 202 : 101 - 106
  • [10] Supramolecular system of podophyllotoxin and hydroxypropyl-β-cyclodextrin: Characterization, inclusion mode, docking calculation, solubilization, stability and cytotoxic activity
    Yang, Li-Juan
    Wang, Shu-Hui
    Zhou, Shu-Ya
    Zhao, Fang
    Chang, Qing
    Li, Min-Yan
    Chen, Wen
    Yang, Xiao-Dong
    MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 76 : 1136 - 1145
12345