Candidemia in a tertiary hospital in northeastern Brazil

被引:27
|
作者
Hinrichsen, Sylvia Lemos [1 ]
Falcao, Erika [2 ]
Santos Vilella, Tatiana Aguiar [1 ]
Colombo, Arnaldo Lopes [3 ]
Nucci, Marcio [4 ]
Moura, Libia [1 ]
Rego, Leandro [5 ]
Lira, Conceicao [1 ]
Almeida, Luciano [2 ]
机构
[1] Univ Fed Pernambuco, Nucleo Ensino Pesquisa & Assistencia Infectol, Recife, PE, Brazil
[2] Dept Microbiol, Recife, PE, Brazil
[3] Univ Fed Sao Paulo, Disciplina Doencas Infecciosas & Parasitarias, Sao Paulo, Brazil
[4] Univ Fed Rio de Janeiro, Hosp Univ Clementino Fraga Filho, Lab Micol, Rio De Janeiro, Brazil
[5] Univ Fed Pernambuco, Dept Estat, Recife, PE, Brazil
关键词
Candidemia; Candida species; Candida non-albicans; Incidence;
D O I
10.1590/S0037-86822008000400014
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
We conducted a prospective, observational, laboratory-based study on candidemia to investigate the incidence of candidemia, species distribution and clinical conditions between September 2003 and March 2004 in a private tertiary hospital in Recife, northeastern Brazil. Cases of candidemia were defined as occurrences of isolation of Candida spp from blood cultures. The incidence rate was calculated per 1,000 admissions. A total of 5,532 patients were admitted to the hospital during the study period, and 1,745 blood cultures were processed. Twenty-one episodes of candidemia were observed in 18 patients. The incidence rate of candidemia was 3.9 episodes per 1,000 admissions. Non-albicans species accounted for more than 50% of the cases, and Candida parapsilosis (33%) and Candida tropicalis (24%) predominated. Eleven (61%) patients died. The incidence of candidemia was higher than that observed in a Brazilian multicenter study. Candidemia was caused predominantly by non-albicans species.
引用
收藏
页码:394 / 398
页数:5
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