Atherosclerosis and infection: is the jury still not in?

被引:2
|
作者
Chatzidimitriou, Dimitrios [1 ]
Kirmizis, Dimitrios [2 ]
Gavriilaki, Eleni [2 ]
Chatzidimitriou, Maria [3 ]
Malisiovas, Nikolaos [1 ]
机构
[1] Aristotle Univ Thessaloniki, Dept Microbiol, GR-54006 Thessaloniki, Greece
[2] Aristotle Univ Thessaloniki, Sch Med, GR-54006 Thessaloniki, Greece
[3] Alexandr Technol Educ Inst, Thessaloniki, Greece
关键词
atherosclerosis; Chlamydophila pneumoniae; cytomegalovirus; Helicobacter pylori; infection; mechanisms; periodontal pathogen; CORONARY-HEART-DISEASE; CHLAMYDIA-PNEUMONIAE INFECTION; ACUTE MYOCARDIAL-INFARCTION; SMOOTH-MUSCLE-CELLS; HERPES-SIMPLEX-VIRUS; C-REACTIVE PROTEIN; RANDOMIZED CONTROLLED-TRIALS; CARDIOVASCULAR RISK-FACTORS; HETEROZYGOTE MURINE MODEL; POLYMERASE-CHAIN-REACTION;
D O I
10.2217/FMB.12.87
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Atherosclerosis is a chronic inflammatory process accounting for increased cardiovascular and cerebrovascular morbidity and mortality. A wealth of recent data has implicated several infectious agents, mainly Chlamydophila pneumoniae, Helicobacter pylori, CMV and periodontal pathogens, in atherosclerosis. Thus, we sought to comprehensively review the available data on the topic, exploring in particular the pathogenetic mechanisms, and discuss anticipated future directions.
引用
收藏
页码:1217 / 1230
页数:14
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