Long-term results of Gamma Knife radiosurgery for facial nerve schwannomas

被引:2
|
作者
Akyoldas, Goktug [1 ]
Sirin, Alperen [2 ]
Yilmaz, Meltem [3 ]
Sengoz, Meric [4 ]
Peker, Selcuk [1 ]
机构
[1] Koc Univ, Sch Med, Dept Neurosurg, Istanbul, Turkey
[2] Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Istanbul, Turkey
[3] Acibadem Mehmet Ali Aydinlar Univ, Med Biotechnol, Istanbul, Turkey
[4] Acibadem Mehmet Ali Aydinlar Univ, Dept Radiat Oncol, Sch Med, Istanbul, Turkey
关键词
Facial nerve schwannoma; Gamma Knife; oncology; stereotactic radiosurgery; FRACTIONATED STEREOTACTIC RADIOTHERAPY; CASE SERIES; MANAGEMENT; OUTCOMES; SURGERY; NEUROMAS;
D O I
10.1080/01616412.2020.1796379
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective Long-term outcomes of eleven cases of facial nerve schwannoma were evaluated and the related literature was reviewed to determine the efficacy of Gamma Knife radiosurgery for treating patients with facial nerve schwannoma. Methods Eleven patients with facial nerve schwannoma (7 women and 4 men; mean age, 44.2 years; range, 19-73 years) underwent Gamma Knife radiosurgery. The most common symptoms were facial palsy (n = 10) and hearing loss (n = 7). Five patients presented with headache. Two patients had undergone prior resection. The patients' clinical and radiographic data were evaluated retrospectively. Results For the 11 cases of facial nerve schwannoma, mean tumor volume was 3.1 cm(3) (range, 0.4-7.4 cm(3)) and the mean marginal dose applied was 11.9 Gy (range, 11-13 Gy). The mean follow-up period was 84.3 months (range, 66-117 months). Tumor control was achieved in all patients. At the time of writing, four patients experienced tumor volume regression and the other seven were in stable condition. During follow-up, nine patients experienced no change in their facial function, two experienced deteriorated facial function, and none developed new facial palsy. Ten patients who had serviceable hearing prior to Gamma Knife radiosurgery retained their hearing. Conclusions Gamma Knife radiosurgery achieves excellent results with respect to tumor control for 7 years on average. In addition, Gamma Knife radiosurgery provides good results in facial nerve and hearing function at long term. Our series demonstrates that Gamma Knife radiosurgery is an effective and safe treatment for patients with either primary or residual facial nerve schwannoma.
引用
收藏
页码:1055 / 1060
页数:6
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