Ubiquitin-induced phase separation of p62/SQSTM1

被引：10

作者：

Herhaus, Lina ^{[1
]}

Dikic, Ivan ^{[1
,2
]}

机构：

[1] Goethe Univ, Inst Biochem 2, Sch Med, Theodor Stern Kai 7, D-60590 Frankfurt, Germany

[2] Goethe Univ Frankfurt, Buchmann Inst Mol Life Sci, Riedberg Campus,Max von Laue Str 15, D-60438 Frankfurt, Germany

来源：

CELL RESEARCH | 2018年 / 28卷 / 04期

关键词：

SELECTIVE AUTOPHAGY; PROTEINS; PHOSPHORYLATION;

D O I：

10.1038/s41422-018-0030-x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

During the process of autophagy, cytoplasmic material is targeted by autophagic receptor proteins, which were thought to segregate the cargo by forming aggregates. Recent evidence suggests that cargo is actually concentrated and segregated into protein condensates by ubiquitin chain-induced phase separation of autophagy receptor

引用

页码：389 / 390

页数：2

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