Evaluation of cognitive functions in individuals with synthetic cannabinoid use disorder and comparison to individuals with cannabis use disorder

被引:16
|
作者
Cengel, Hanife Yilmaz [1 ]
Bozkurt, Muge [1 ]
Evren, Cuneyt [1 ]
Umut, Gokhan [1 ]
Keskinkilic, Cahit [2 ]
Agachanli, Ruken [1 ]
机构
[1] Bakirkoy Training & Res Hosp Psychiat Neurol & Ne, Res Treatment & Training Ctr Alcohol & Subst Depe, Istanbul, Turkey
[2] Bakirkoy Training & Res Hosp Psychiat Neurol & Ne, Dept Neuropsychol, Istanbul, Turkey
关键词
Synthetic cannabinoid; Cannabis; Cognitive functions; Spice; EPISODIC MEMORY; CB1; RECEPTORS; HUMANS; ATTENTION; PERFORMANCE; CEREBELLUM; BRAIN; INHIBITION; DEPENDENCE; MARIJUANA;
D O I
10.1016/j.psychres.2018.01.046
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The use of synthetic cannabinoid has been increasing throughout the world and has become a major public health problem. The present study aims to investigate the attention, memory, visuospatial and executive functions in individuals with synthetic cannabinoid use disorder and compare the results with findings obtained from individuals with cannabis use disorder and healthy volunteers with no substance use. Fifty-two patients with synthetic cannabinoid use disorder, 45 patients with cannabis use disorder and 48 healthy control group males were included in the study. The neuropsychological test battery was designed to involve ten studies evaluating a large series of cognitive functions. Impairments in attention, memory, executive and visuospatial functions were identified in individuals with synthetic cannabinoid use disorder and these impairments were found to be significantly greater than in individuals with cannabis use disorder and healthy controls. In line with the data obtained from this study; the evaluation of each cognitive function with more comprehensive test batteries and supporting these evaluations with sensitive brain imaging studies are important topics for future research.
引用
收藏
页码:46 / 54
页数:9
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