Eurocode 8 is applied far the complete design of 26 multi-storey reinforced concrete buildings to study its operationality and compare the implications of trading strength for ductility through designing the same structure for a different Ductility Class. The difference between the conventional full Capacity Design of columns in bending and the relaxed one allowed by Eurocode 8 is quantified, and the implications on the column capacities are examined. About half of the designed buildings, representative of the class of regular frames, are subjected to nonlinear dynamic response analyses to spectrum-compatible motions with intensities up to twice that of the design motion. Nonlinear modeling is very simple, but gives satisfactory agreement with available quasistatic or pseudodynamic test results on full scale structures. Results show that the three Ductility Classes of Eurocode 8 are essentially equivalent in terms of material quantities and seismic performance. Within the limitations of the nonlinear modelling, the response results suggest very satisfactory performance of structures designed to Eurocode 8, even under twice the design motion intensity. Softening of the structure due to concrete cracking and steel yielding significantly reduces the seismic force demands and contributes to the satisfactory performance, despite the increased P-delta effects. Another important contributor to the good performance is the significant overstrength of the members considered in the analyses with their average as-built properties. Beam overstrength due to the contribution of the slab to flexurd capacity is large enough to overcome the effects of the application of the relaxed Capacity Design rule to columns in bending. However, the resulting column plastic hinging does not lead to drift concentrations suggesting formation of storey-way mechanisms.