Switching to aflibercept treatment resulted in greater tumor responses than continuous bevacizumab treatment in patient-derived xenograft models of colorectal cancer.

被引:5
|
作者
Chiron, Marielle [1 ]
Bagley, Rebecca G. [2 ]
Pollard, Jack [2 ]
Henry, Christophe [1 ]
Mankoo, Parminder [2 ]
Vincent, Loic [1 ]
Geslin, Catherine [1 ]
Kloss, Tatjana [3 ]
Bergstrom, Donald A. [2 ]
机构
[1] Sanofi, Vitry Sur Seine, France
[2] Sanofi, Cambridge, MA USA
[3] Oncotest GmbH, Freiburg, Germany
关键词
D O I
10.1158/1535-7163.TARG-13-B2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B2
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Aflibercept inhibits tumor growth more effectively than bevacizumab in patient-derived xenograft (PDX) models of colorectal cancer
    Chiron, M.
    Bagley, R. G.
    Pollard, J. R.
    Henry, C.
    Mankoo, P. K.
    Vincent, L.
    Geslin, C.
    Amalou, Z.
    Baltes, N.
    Bergstrom, D. A.
    [J]. EUROPEAN JOURNAL OF CANCER, 2013, 49 : S497 - S498
  • [2] Differential Antitumor Activity of Aflibercept and Bevacizumab in Patient-Derived Xenograft Models of Colorectal Cancer
    Chiron, Marielle
    Bagley, Rebecca G.
    Pollard, Jack
    Mankoo, Parminder K.
    Henry, Christophe
    Vincent, Loic
    Geslin, Catherine
    Baltes, Nina
    Bergstrom, Donald A.
    [J]. MOLECULAR CANCER THERAPEUTICS, 2014, 13 (06) : 1636 - 1644
  • [3] Patient-derived xenograft models—the future of personalised cancer treatment
    Jenna Bhimani
    Katie Ball
    Justin Stebbing
    [J]. British Journal of Cancer, 2020, 122 : 601 - 602
  • [4] Characterization of patient-derived xenograft models of endometrial cancer.
    Zhang, Yuping
    Devor, Eric J.
    Dai, Donghai
    Gonzalez-Bosquet, Jesus
    Thiel, Kristina W.
    Leslie, Kimberly K.
    [J]. CLINICAL CANCER RESEARCH, 2021, 27 (03)
  • [5] Patient-derived xenograft models-the future of personalised cancer treatment
    Bhimani, Jenna
    Ball, Katie
    Stebbing, Justin
    [J]. BRITISH JOURNAL OF CANCER, 2020, 122 (05) : 601 - 602
  • [6] Use of patient-derived xenograft mouse models in cancer research and treatment
    Yada, Erica
    Wada, Satoshi
    Yoshida, Shintaro
    Sasada, Tetsuro
    [J]. FUTURE SCIENCE OA, 2018, 4 (03):
  • [7] Enhanced activity of aflibercept compared to bevacizumab in a patient-derived xenograft colorectal cancer model is associated with reduced tumor vascularity in humanized VEGF mice
    Abrahams, Cristina L.
    Winters, Laura D.
    Li, Baosheng
    Parveen, Asma A.
    Kloss, Tatjana
    Bagley, Rebecca G.
    Bergstrom, Donald A.
    Thurston, Gavin
    Chiron, Marielle
    [J]. CANCER RESEARCH, 2014, 74 (19)
  • [8] Patient-derived xenograft models for personalized medicine in colorectal cancer
    Jun Xie
    Yan Lin
    [J]. Clinical and Experimental Medicine, 2020, 20 : 167 - 172
  • [9] Patient-derived xenograft models for personalized medicine in colorectal cancer
    Xie, Jun
    Lin, Yan
    [J]. CLINICAL AND EXPERIMENTAL MEDICINE, 2020, 20 (02) : 167 - 172
  • [10] Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models
    Prasetyanti, Pramudita R.
    van Hooff, Ander R.
    van Herwaarden, Tessa
    de Vries, Nathalie
    Kalloe, Kieshen
    Rodermond, Hans
    van Leersum, Ronald
    de Jong, Joan H.
    Franitza, Marek
    Nuernberg, Peter
    Todaro, Matilde
    Stassi, Giorgio
    Medema, Jan Paul
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2019, 144 (02) : 366 - 371