Recombinant protein expression for therapeutic applications

被引：235

作者：

Andersen, DC ^{[1
]}

Krummen, L ^{[1
]}

机构：

[1] Genentech Inc, Cell Culture & Fermentat Res & Dev, San Francisco, CA 94080 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0958-1669(02)00300-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In recent years, the number of recombinant proteins used for therapeutic applications has increased dramatically. Many of these applications involve complex glycoproteins and antibodies with relatively high production needs. These demands have driven the development of a variety of improvements in protein expression technology, particularly involving mammalian and microbial culture systems.

引用

页码：117 / 123

页数：7

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