Cloning of a putative gamma-aminobutyric acid (GABA) receptor subunit rho 3 cDNA

被引:85
|
作者
Ogurusu, T
Shingai, R
机构
[1] Dept. of Comp. and Info. Science, Faculty of Engineering, Iwate University, Morioka, Iwate
关键词
gamma-aminobutyric acid receptor; GABA; receptor; cDNA; p3;
D O I
10.1016/0167-4781(95)00205-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cloned cDNA encoding a putative member of GABA receptor rho-subunit class was isolated from rat-retina-mRNA-derived libraries. The cDNA encodes a signal peptide of 21 amino acids followed by the mature rho 3 subunit sequence of 443 amino acids. The proposed amino acid sequence exhibits 63 and 61% homology to the previously-reported human rho 1 and rat rho 2 sequences, respectively. Northern blot analysis demonstrated the expression of mRNA for rho 3 subunit in retina.
引用
收藏
页码:15 / 18
页数:4
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