Aging and Bone Health in Individuals with Developmental Disabilities

被引:22
|
作者
Jasien, Joan [1 ,2 ]
Daimon, Caitlin M. [1 ]
Maudsley, Stuart [3 ]
Shapiro, Bruce K. [2 ]
Martin, Bronwen [1 ]
机构
[1] NIA, Metab Unit, NIH, Baltimore, MD 21224 USA
[2] Kennedy Krieger Inst, Dept Neurol & Neurodev, Baltimore, MD 21224 USA
[3] NIA, Receptor Pharmacol Unit, NIH, Baltimore, MD 21224 USA
基金
美国国家卫生研究院;
关键词
SEVERE CEREBRAL-PALSY; MINERAL DENSITY; MENTAL-RETARDATION; RISK-FACTORS; INTELLECTUAL DISABILITY; DOWNS-SYNDROME; MUSCLE STRENGTH; OLDER-ADULTS; CHILDREN; OSTEOPOROSIS;
D O I
10.1155/2012/469235
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Low bone mass density (BMD), a classical age-related health issue and a known health concern for fair skinned, thin, postmenopausal Caucasian women, is found to be common among individuals with developmental/intellectual disabilities (D/IDs). It is the consensus that BMDis decreased in both men and women with D/ID. Maintaining good bone health is important for this population as fractures could potentially go undetected in nonverbal individuals, leading to increased morbidity and a further loss of independence. This paper provides a comprehensive overview of bone health of adults with D/ID, their risk of fractures, and how this compares to the general aging population. We will specifically focus on the bone health of two common developmental disabilities, Down syndrome (DS) and cerebral palsy (CP), and will discuss BMD and fracture rates in these complex populations. Gaining a greater understanding of how bone health is affected in individuals with D/ID could lead to better customized treatments for these specific populations.
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页数:10
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