Human protein C concentrates in adult septic patients

被引：5
|
作者：
Landoni, Giovanni [1 ]
Crivellari, Martina [1 ]
Monti, Giacomo [1 ]
Gerli, Chiara [1 ]
Silvani, Paolo [1 ]
Zangrillo, Alberto [1 ]
机构：
[1] Ist Sci San Raffaele, Dept Cardiothorac Anesthesia & Intens Care, I-20132 Milan, Italy
来源：
SIGNA VITAE | 2008年 / 3卷 / 02期
关键词：
sepsis; protein C; cardiac surgery;
D O I：
10.22514/SV32.102008.1
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Some case reports and case series suggest that protein C concentrates may improve the outcome in patients with congenital or acquired protein C deficiency (not only in those with sepsis induced purpura fulminans). We reviewed the published literature on the use of protein C concentrates in adult septic patients and found that it is limited to less than 70 patients reported in observational studies with a 70% survival, and added our personal experience (two adult patients with sepsis and contraindications to recombinant activated protein C).
引用
收藏
页码：13 / 17
页数：5
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