Transmitted drug resistance in French HIV-2-infected patients

被引：12

作者：

Charpentier, Charlotte ^{[1
]}

Visseaux, Benoit ^{[1
]}

Benard, Antoine ^{[2
]}

Peytavin, Gilles ^{[3
]}

Damond, Florence ^{[1
]}

Roy, Celine ^{[2
]}

Taieb, Audrey ^{[2
]}

Chene, Genevieve ^{[2
]}

Matheron, Sophie ^{[4
]}

Brun-Vezinet, Francoise ^{[1
]}

Descamps, Diane ^{[1
]}

机构：

[1] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP, HUPNVS,PRES Sorbonne Paris Cite,Lab Virol, Paris, France

[2] Bordeaux Segalen Univ, ISPED, INSERM, U897, Bordeaux, France

[3] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP, HUPNVS,PRES Sorbonne Paris Cite,Lab Pharmacol, Paris, France

[4] Univ Paris 07, Grp Hosp Bichat Claude Bernard, AP HP,HUPNVS,PRES Sorbonne Paris Cite, Serv Malad Infect & Trop, Paris, France

来源：

AIDS | 2013年 / 27卷 / 10期

关键词：

IMMUNODEFICIENCY-VIRUS TYPE-2; HIV-2; INFECTED-PATIENTS; ANTIRETROVIRAL THERAPY; PROTEASE INHIBITORS; MUTATIONS; SURVEILLANCE; PREVALENCE; SUSCEPTIBILITY; MULTICENTER; SELECTION;

D O I：

10.1097/QAD.0b013e32836207f3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in protease, not in reverse transcriptase. In this series, 10% of patients displayed X4/dual-mixed viruses. These findings classified the rate of transmitted drug resistance in the HIV-2 French Cohort as low prevalence.

引用

页码：1671 / 1674

页数：4

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