Bioconjugated Gold Nanoparticle for Rapid Capture and Targeted Photothermal Lysis of Pathogenic Bacteria

Outbreak of food poisoning by Salmonella and E. colt bacteria are very common in this world. On the other hand, multiple drug resistant Salmonella enterica serover typhimurium definitive type 104 (DT104) is at present an emerging threat worldwide. As a result, an ultrasensitive sensing technology for the rapid detection and new approaches for the treatment of infectious bacterial pathogens that do not rely on traditional therapeutic regimes is very urgently required in today's world. This book chapter discusses our recent report on bio-conjugated nanomaterial based strategies for the pathogen detection and photothermal applications. We have focused on the basic concepts and critical properties of the nanostructures that are useful for the pathogen sensing and killing.