TELAPREVIR- BASED THERAPY IN G1 HCV-INFECTED PATIENTS WITH PRIOR NULL RESPONSE, PARTIAL RESPONSE OR RELAPSE TO PEGINTERFERON/RIBAVIRIN: REALIZE TRIAL FINAL RESULTS

被引:0
|
作者
Foster, G. [1 ]
Zeuzem, S. [2 ]
Andreone, P. [3 ]
Pol, S. [4 ,5 ]
Lawitz, E. [6 ]
Diago, M. [7 ]
Roberts, S. [8 ]
Focaccia, R. [9 ]
Younossi, Z. [10 ]
H, A. [11 ]
Heeswijk, R. V. [12 ]
de Meyer, S. [12 ]
Luo, D. [13 ]
Picchio, G. [13 ]
Beumont, M. [12 ]
机构
[1] Queen Mary Univ London, Inst Cell & Mol Sci, London, England
[2] Goethe Univ Frankfurt, Med Ctr, D-60054 Frankfurt, Germany
[3] Univ Bologna, Bologna, Italy
[4] Univ Paris 05, INSERM, U567, Paris, France
[5] Hop Cochin, AP HP, F-75674 Paris, France
[6] Alamo Med Res, San Antonio, TX USA
[7] Hosp Gen Valencia, Valencia, Spain
[8] Alfred Hosp, Dept Gastroenterol, Melbourne, Vic, Australia
[9] Emilio Ribas Infect Dis Inst, Sao Paulo, Brazil
[10] Inova Fairfax Hosp, Ctr Liver Dis, Falls Church, VA USA
[11] Med Univ Warsaw, Warsaw, Poland
[12] Tibotec BVBA, Beerse, Belgium
[13] Tibotec Inc, Titusville, NJ USA
关键词
D O I
10.1136/gutjnl-2011-300857b.3
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
OP03
引用
收藏
页码:A50 / A51
页数:6
相关论文
共 50 条
  • [1] Telaprevir-based therapy in G1 HCV-infected patients with prior null response, partial response or relapse to peginterferon/ribavirin: REALIZE trial final results
    Mullhaupt, Beat
    Zeuzem, Stefan
    Andreone, Pietro
    Pol, Stanislas
    Lawitz, Eric
    Diago, Moises
    Roberts, S.
    Focaccia, Roberto
    Younossi, Zobair
    Foster, Graham
    Horban, Andrzej
    Pockros, Paul. J.
    Van Heeswijk, Rolf
    de Meyer, Sandra
    Luo, Donghan
    Picchio, Gaston
    Beumont, Maria
    SWISS MEDICAL WEEKLY, 2011, 141 : 6S - 6S
  • [2] Telaprevir-Based Regimen in Genotype 1 Hepatitis C Virus-Infected Patients With Prior Null Response, Partial Response or Relapse to Peginterferon/Ribavirin: REALIZE Trial Final Results
    Pockros, Paul
    Zeuzem, Stefan
    Lawitz, Eric J.
    Younossi, Zobair M.
    Andreone, Pietro
    Pol, Stanislas
    Diago, Moises
    Roberts, Stuart K.
    Focaccia, Roberto
    Foster, Graham
    Horban, Andrzej
    van Heeswijk, Rolf
    De Meyer, Sandra
    Luo, Don
    Picchio, Gaston
    Beumont-Mauviel, Maria
    GASTROENTEROLOGY, 2011, 140 (05) : S898 - S898
  • [3] REALIZE TRIAL FINAL RESULTS: TELAPREVIR-BASED REGIMEN FOR GENOTYPE 1 HEPATITIS C VIRUS INFECTION IN PATIENTS WITH PRIOR NULL RESPONSE, PARTIAL RESPONSE OR RELAPSE TO PEGINTERFERON/RIBAVIRIN
    Zeuzem, S.
    Andreone, P.
    Pol, S.
    Lawitz, E. J.
    Diago, M.
    Roberts, S.
    Focaccia, R.
    Younossi, Z. M.
    Foster, G. R.
    Horban, A.
    Pockros, P. J.
    Van Heeswijk, R.
    de Meyer, S.
    Luo, D.
    Picchio, G.
    Beumont, M.
    JOURNAL OF HEPATOLOGY, 2011, 54 : S3 - S3
  • [4] SVR WITH TELAPREVIR, PEGINTERFERON ALFA-2A AND RIBAVIRIN IN HCV PATIENTS WITH WELL-CHARACTERIZED PRIOR NULL RESPONSE, PARTIAL RESPONSE, VIRAL BREAKTHROUGH OR RELAPSE AFTER PR
    Berg, T.
    McHutchison, J. G.
    Adda, N.
    Poordad, F.
    Shiffman, M. L.
    Ferenci, P.
    Heathcote, J.
    Pawlotsky, J. -M.
    Zeuzem, S.
    Reesink, H.
    Dusheiko, G.
    Martin, E.
    Alexanderian, D.
    George, S.
    Muir, A. J.
    JOURNAL OF HEPATOLOGY, 2010, 52 : S2 - S2
  • [5] Final Results of a Rollover Study Assessing Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Chronic HCV Patients With Well-Characterized Null Response, Partial Response, Viral Breakthrough, or Relapse After Prior PR Treatment
    Muir, Andrew J.
    Poordad, Fred
    Adda, Nathalie
    Shiffman, Mitchell L.
    Berg, Thomas
    Ferenci, Peter
    Heathcote, E. Jenny
    Pawlotsky, Jean-Michel
    Zeuzem, Stefan
    Reesink, Henk W.
    Dusheiko, Geoffrey M.
    Martin, Emily C.
    Alexanderian, David
    George, Shelley
    McHutchison, John
    GASTROENTEROLOGY, 2010, 138 (05) : S782 - S783
  • [6] Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1
    Akuta, Norio
    Suzuki, Fumitaka
    Seko, Yuya
    Kawamura, Yusuke
    Sezaki, Hitomi
    Suzuki, Yoshiyuki
    Hosaka, Tetsuya
    Kobayashi, Masahiro
    Kobayashi, Mariko
    Saitoh, Satoshi
    Arase, Yasuji
    Ikeda, Kenji
    Kumada, Hiromitsu
    JOURNAL OF MEDICAL VIROLOGY, 2012, 84 (07) : 1097 - 1105
  • [7] Insulin resistance and response to telaprevir plus peginterferon α and ribavirin in treatment-naive patients infected with HCV genotype 1
    Serfaty, Lawrence
    Forns, Xavier
    Goeser, Tobias
    Ferenci, Peter
    Nevens, Frederik
    Carosi, Giampiero
    Drenth, Joost P.
    Lonjon-Domanec, Isabelle
    DeMasi, Ralph
    Picchio, Gaston
    Beumont, Maria
    Marcellin, Patrick
    GUT, 2012, 61 (10) : 1473 - 1480
  • [8] Randomized study of danoprevir/ritonavir-based therapy for HCV genotype 1 patients with prior partial or null responses to peginterferon/ribavirin
    Feld, Jordan J.
    Jacobson, Ira M.
    Jensen, Donald M.
    Foster, Graham R.
    Pol, Stanislas
    Tam, Edward
    Jablkowski, Maciej
    Berak, Hanna
    Vierling, John M.
    Yoshida, Eric M.
    Perez-Gomez, Hector R.
    Scalori, Astrid
    Hooper, Gregory J.
    Tavel, Jorge A.
    Navarro, Mercidita T.
    Shahdad, Saba
    Kulkarni, Rohit
    Le Pogam, Sophie
    Najera, Isabel
    Eng, Simon
    Lim, Chin Yin
    Shulman, Nancy S.
    Yetzer, Ellen S.
    JOURNAL OF HEPATOLOGY, 2015, 62 (02) : 294 - 302
  • [9] Boceprevir for chronic HCV genotype 1 infection in patients with prior treatment failure to peginterferon/ribavirin, including prior null response
    Vierling, John M.
    Davis, Mitchell
    Flamm, Steven
    Gordon, Stuart C.
    Lawitz, Eric
    Yoshida, Eric M.
    Galati, Joseph
    Luketic, Velimir
    McCone, Jonathan
    Jacobson, Ira
    Marcellin, Patrick
    Muir, Andrew J.
    Poordad, Fred
    Pedicone, Lisa D.
    Albrecht, Janice
    Brass, Clifford
    Howe, Anita Y. M.
    Colvard, Lynn Y.
    Helmond, Frans A.
    Deng, Weiping
    Treitel, Michelle
    Wahl, Janice
    Bronowicki, Jean-Pierre
    JOURNAL OF HEPATOLOGY, 2014, 60 (04) : 748 - 756
  • [10] Randomized study of danoprevir/ritonavir-based therapy for HCV genotype 1 patients with prior partial or null responses to peginterferon/ribavirin
    Song, Ze-Zhou
    JOURNAL OF HEPATOLOGY, 2015, 63 (03) : 769 - 770