Evolution of HIV and HCV coinfected children receiving long-term lopinavir/ritonavir-based antiretroviral therapy

被引：0
|
作者：
Larru, Beatriz [1 ]
Resino, Salvador [1 ,2 ]
Bellon, Jose M. [1 ]
Isabel de Jose Gomez, M. [3 ]
Fortuna, Claudia [4 ]
Munoz-Fernandez, M. Angeles [1 ]
机构：
[1] Hosp Gen Univ Gregorio Maranon, Lab Inmunobiol Mol, Madrid 28007, Spain
[2] Inst Salud Carlos III, Ctr Nacl Microbiol, Madrid, Spain
[3] Hosp Univ La Paz, Serv Inmunopediat, Madrid, Spain
[4] Hosp San Joan de Deu, Serv Inmunopediat, Barcelona, Spain
来源：
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2008年 / 26卷 / 07期
关键词：
HIV; HCV; LPV/r; HAART; children;
D O I：
10.1157/13125640
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
INTRODUCTION. There are few studies investigating the effect of HCV coinfection on HIV-related disease among children. METHODS. We studied 5 HIV/HCV coinfected children receiving an LPV/r-containing HAART regimen. Their evolution was compared with a control group of 72 HIV-infected children. RESULTS. All 5 HIV/HCV-coinfected children achieved sustained immune recovery during the study. Moreover, they showed better viral suppression than the control group. None of the 5 HIV/HCV-coinfected children experienced any adverse effects with the use of LPV/r. CONCLUSION. HIV/HCV coinfection does not reduce the benefits obtained from HAART.
引用
收藏
页码：426 / 429
页数：4
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