pH-responsive gold nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor delivery

被引：31
|
作者：
Nam, Jutaek [1 ]
Ha, Yeong Su [2 ]
Hwang, Sekyu [1 ]
Lee, Woonghee [2 ]
Song, Jaejung [3 ]
Yoo, Jeongsoo [2 ]
Kim, Sungjee [1 ,3 ]
机构：
[1] Pohang Univ Sci & Technol POSTECH, Dept Chem, Pohang 790784, South Korea
[2] Kyungpook Natl Univ, Sch Med, Dept Mol Med, Taegu 700422, South Korea
[3] POSTECH, Sch Interdisciplinary Biosci & Bioengn, Pohang, South Korea
来源：
NANOSCALE | 2013年 / 5卷 / 21期
基金：
新加坡国家研究基金会;
关键词：
PLATFORM; THERAPY; RELEASE; ABSORPTION; SIZE;
D O I：
10.1039/c3nr03698g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a pH-responsive gold nanoparticles-in-liposome hybrid nanostructure, which effectively combines the pH-responsive assembly and surface plasmon property changes of 'smart' gold nanoparticles and enhanced systemic circulation and tumor accumulation of the PEG-grafted liposomes.
引用
收藏
页码：10175 / 10178
页数：4
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