Neuroimaging in Functional Movement Disorders

被引:36
|
作者
Roelofs, Jacob J. [1 ,2 ]
Teodoro, Tiago [2 ,3 ]
Edwards, Mark J. [2 ,4 ]
机构
[1] North Bristol NHS Trust, Southmead Hosp, Bristol, Avon, England
[2] St Georges Univ London, Inst Mol & Clin Sci, Neurosci Res Ctr, Cranmer Terrace, London SW17 0QT, England
[3] Univ Lisbon, Inst Med Mol, Fac Med Lisboa, Lisbon, Portugal
[4] St Georges Univ Hosp, Atkinson Morley Reg Neurosci Ctr, London, England
基金
英国医学研究理事会;
关键词
Functional movement disorders; Conversion disorder; Psychogenic; MRI; fMRI; Imaging; MOTOR INHIBITION; SPECT; PARKINSONISM; NEUROLOGY; TREMOR;
D O I
10.1007/s11910-019-0926-y
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose of Review Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping to unravel the pathophysiology of this enigmatic condition. Recent Findings In recent years, there has been a shift in thinking about functional movement disorder, away from a focus on high-level psychological precipitants as in Freudian conversion theories, or even an implicit belief they are put-on' for secondary gain. New research has emphasised novel neurobiological models incorporating emotional processing, self-representation and agency. Summary Neuroimaging has provided new insights into functional movement disorders, supporting emerging neurobiological theories implicating dysfunctional emotional processing, self-image and sense of agency. Recent studies have also found subtle structural brain changes in patients with functional disorders, arguing against a strict functional/structural dichotomy.
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页数:7
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