Trefoil factor-3 is down regulated while CYP24a1 is increased in the ageing rat kidney

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作者
Hultstrom, Michael [1 ,2 ]
Iversen, Bjarne M. [1 ,2 ]
机构
[1] Univ Bergen, Dept Med, Renal Res Grp, Bergen, Norway
[2] Haukeland Hosp, Dept Internal Med, N-5021 Bergen, Norway
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FASEB JOURNAL | 2010年 / 24卷
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Q5 [生物化学]; Q7 [分子生物学];
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071010 ; 081704 ;
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页数:1
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  • [1] Synthesis of 2α-propoxy-1α,25-dihydroxyvitamin D3 and comparison of its metabolism by human CYP24A1 and rat CYP24A1
    Saito, Nozomi
    Suhara, Yoshitomo
    Abe, Daisuke
    Kusudo, Tatsuya
    Ohta, Miho
    Yasuda, Kaori
    Sakaki, Toshiyuki
    Honzawa, Shinobu
    Fujishima, Toshie
    Kittaka, Atsushi
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (13) : 4296 - 4301
  • [2] Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activity
    Tieu, Elaine W.
    Tang, Edith K. Y.
    Chen, Jianjun
    Li, Wei
    Nguyen, Minh N.
    Janjetovic, Zorica
    Slominski, Andrzej
    Tuckey, Robert C.
    [J]. BIOCHEMICAL PHARMACOLOGY, 2012, 84 (12) : 1696 - 1704
  • [3] CYP24A1 Exacerbated Activity during Diabetes Contributes to Kidney Tubular Apoptosis via Caspase-3 Increased Expression and Activation
    Tourigny, Alexandre
    Charbonneau, Fredrick
    Xing, Paul
    Boukrab, Rania
    Rousseau, Guy
    St-Arnaud, Rene
    Brezniceanu, Marie-Luise
    [J]. PLOS ONE, 2012, 7 (10):
  • [4] C-25 hydroxylation of 1α,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1):: metabolism studies with human keratinocytes and rat recombinant CYP24A1
    Astecker, N
    Bobrovnikova, EA
    Omdahl, JL
    Gennaro, L
    Vouros, P
    Schuster, I
    Uskokovic, MR
    Ishizuka, S
    Wang, GC
    Reddy, GS
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2004, 431 (02) : 261 - 270
  • [5] Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1
    Tieu, Elaine W.
    Li, Wei
    Chen, Jianjun
    Kim, Tae-Kang
    Ma, Dejian
    Slominski, Andrzej T.
    Tuckey, Robert C.
    [J]. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2015, 149 : 153 - 165
  • [6] Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies
    Tannour-Louet, Mounia
    Lewis, Shaye K.
    Louet, Jean-Francois
    Stewart, Julie
    Addai, Josephine B.
    Sahin, Aysegul
    Vangapandu, Hima V.
    Lewis, Annisa L.
    Dittmar, Kristin
    Pautler, Robia G.
    Zhang, Lixin
    Smith, Roy G.
    Lamb, Dolores J.
    [J]. FASEB JOURNAL, 2014, 28 (01): : 364 - 372
  • [7] Metabolic Stability of 3-Epi-1α, 25-Dihydroxyvitamin D3 Over 1 α 25-Dihydroxyvitamin D3: Metabolism and Molecular Docking Studies Using Rat CYP24A1
    Rhieu, Steve Y.
    Annalora, Andrew J.
    Wang, Guochun
    Flarakos, Caroline C.
    Gathungu, Rose M.
    Vouros, Paul
    Sigueeiro, Rita
    Mourino, Antonio
    Schuster, Inge
    Palmore, G. Tayhas R.
    Reddy, G. Satyanarayana
    [J]. JOURNAL OF CELLULAR BIOCHEMISTRY, 2013, 114 (10) : 2293 - 2305
  • [8] Phorbol esters enhance 1α,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24A1) gene expression through ERK-mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells
    Jiang, Yan
    Fleet, James C.
    [J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2012, 361 (1-2) : 31 - 39
  • [9] High glucose upregulates CYP24A1 expression which attenuates the ability of 1,25(OH)2D3 to increase NGF secretion in a rat Schwann cell line RSC96
    Zhou, Yi-Kun
    Liang, Zhi
    Guo, Yan
    Zhang, Hua-Tang
    Wang, Kun-Hua
    [J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2015, 404 (0C) : 75 - 81
  • [10] Activating ERK Signaling enhances 1alpha, 25(OH) 2D3-regulated 25-hydroxyvitamin D-24-hydroxylase (CYP24) gene expression through the transcription factor Sp3 pathway in Caco-2 cells.
    Jiang, Yan
    Fleet, James C.
    [J]. FASEB JOURNAL, 2010, 24