Childhood trauma exposure in substance use disorder patients with and without ADHD

被引：25

作者：

Konstenius, Maija ^{[1
]}

Leifman, Anders ^{[2
]}

van Emmerik-van Oortmerssen, Katelijne ^{[3
,4
]}

van de Glind, Geurt ^{[4
]}

Franck, Johan ^{[1
]}

Moggi, Franz ^{[5
,6
]}

Antoni Ramos-Quiroga, Josep ^{[7
]}

Levin, Frances R. ^{[8
]}

Carpentier, Pieter Jan ^{[9
]}

Skutle, Arvid

Buj, Eli-Torild ^{[10
]}

Kaye, Sharlene ^{[11
]}

Demetrovics, Zsolt ^{[12
]}

Barta, Csaba ^{[13
]}

Auriecomb, Marc ^{[14
]}

Fatseas, Melina ^{[14
]}

Johnson, Brian ^{[15
,16
]}

Faraone, Stephen V. ^{[15
,16
]}

Allsop, Steve ^{[17
]}

Carruthers, Susan ^{[17
]}

Schoevers, Robert A. ^{[18
]}

Verspreet, Sofie ^{[19
]}

Dom, Geert ^{[19
]}

Koeter, Maarten W. J. ^{[4
]}

van den Brink, Wim ^{[4
]}

机构：

[1] Karolinska Inst, Dept Clin Neurosci, Div Psychiat, Stockholm, Sweden

[2] Stockholm Ctr Dependency Disorders, Stockholm, Sweden

[3] Arkin, Amsterdam, Netherlands

[4] Univ Amsterdam, Acad Med Ctr, Amsterdam Inst Addict Res, Dept Psychiat, Amsterdam, Netherlands

[5] Univ Bern, Univ Hosp Psychiat, Bern, Switzerland

[6] Univ Fribourg, Dept Psychol, Fribourg, Switzerland

[7] CIBERSAM, Hosp Univ Vall Hebron, Dept Psychiat, Servei Psiquiatria, Madrid, Spain

[8] Columbia Univ, New York State Psychiat Inst, New York, NY USA

[9] Reinier Arket Grp, sHertogenbosch, Netherlands

[10] Bergen Clin Fdn, Bergen, Norway

[11] Univ New South Wales, Natl Drug & Alcohol Res Ctr, Sydney, NSW, Australia

[12] Eotvos Lorand Univ, Inst Psychol, Budapest, Hungary

[13] Semmelweis Univ, Inst Med Chem Mol Biol & Pathobiochem, Budapest, Hungary

[14] Univ Bordeaux, Dept Adaddictol, Lab Psychiat, Bordeaux, France

[15] SUNY Upstate Med Univ, Dept Psychiat, Syracuse, NY USA

[16] SUNY Upstate Med Univ, Dept Neurosci & Physiol, Syracuse, NY USA

[17] Curtin Univ Technol, Natl Drug Res Inst, Perth, WA, Australia

[18] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands

[19] PC Alexian Bros, Collaborat Antwerp Psychiat Res Inst CAPRI UA, Boechout, Belgium

来源：

ADDICTIVE BEHAVIORS | 2017年 / 65卷

关键词：

Childhood trauma; Substance use disorders; Comorbidity; ADHD; DEFICIT HYPERACTIVITY DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; POSTTRAUMATIC-STRESS-DISORDER; PSYCHIATRIC-DISORDERS; SEXUAL-ABUSE; DEPENDENCE SEVERITY; CONDUCT DISORDER; MENTAL-DISORDERS; PHYSICAL ABUSE; ADULT ADHD;

D O I：

10.1016/j.addbeh.2016.10.016

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Background: Childhood trauma exposure (CTE) is frequently reported by those with substance use disorders (SUDs). SUDs also frequently co-occur with attention deficit hyperactivity disorder (ADHD). Objective: To investigate the role of childhood trauma exposure (CTE) in the presence and the persistence of ADHD'in treatment seeking SUD patients. Method: Data was derived from the International ADHD in Substance Use Disorder Prevalence (IASP) study. A structured interview was administered to 1274 treatment-seeking SUD patients aged 18 to 65. Results: CTE was present in 53.5% of the patients and comorbid adult ADHD in 14.1%. CTE was significantly associated with ADHD: the prevalence of adult ADHD with and without CTE was 19.4% and 8.5% (OR adjusted for age, gender, main substance of abuse, BPD, and ASPD 1.91 [95% C11.29-2.81]). CTE was not associated with the severity of adult ADHD or with the persistence of childhood ADHD into adulthood. Conclusions: CTE is common in SUD patients and associated with adult ADHD but not with the persistence of childhood ADHD into adulthood. These findings suggest that the increased rate of adult ADHD in SUD patients with CTE is not the consequence of a negative effect of CTE on:the persistence of childhood ADHD into adulthood, but a direct expression of the high rate of childhood ADHD in SUD patients with CTE. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：118 / 124

页数：7

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