Quality of Life in Lung Transplantation

被引:64
|
作者
Singer, Jonathan P. [1 ,2 ]
Singer, Lianne G. [3 ,4 ]
机构
[1] UC San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94117 USA
[2] UC San Francisco, Cardiovasc Res Inst, San Francisco, CA 94117 USA
[3] Univ Hlth Network, Dept Med, Div Resp Med, Toronto, ON, Canada
[4] Univ Toronto, Toronto, ON, Canada
关键词
lung transplantation; health-related quality of life; utility; disability; patient-reported outcomes; BRONCHIOLITIS-OBLITERANS-SYNDROME; OBSTRUCTIVE PULMONARY-DISEASE; FORM HEALTH SURVEY; INTERNATIONAL-SOCIETY; EXERCISE PERFORMANCE; COST-EFFECTIVENESS; FUNCTIONAL STATUS; SOCIAL SUPPORT; HEART; PREDICTORS;
D O I
10.1055/s-0033-1348470
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Improving health-related quality of life is an important goal of lung transplantation. This review describes background concepts, including definitions, measurement and interpretation of health-related quality of life (HRQL), and other patient-reported outcomes. Lung transplantation is associated with dramatic and sustained improvements in HRQL, particularly in measures of physical health and functioning. Physical rehabilitation may augment the early improvements in HRQL, whereas bronchiolitis obliterans syndrome and psychological conditions have a negative impact. More research is needed, particularly longitudinal, multicenter studies, to better understand the trajectory and determinants of HRQL after lung transplantation, and the impact of targeted interventions to improve HRQL.
引用
收藏
页码:421 / 430
页数:10
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