Cancer immunotherapy: exploiting neoepitopes

被引:16
|
作者
Platten, Michael [1 ,2 ,3 ]
Offringa, Rienk [4 ,5 ]
机构
[1] German Canc Res Ctr, DKTK Clin Cooperat Unit Neuroimmunol & Brain Tumo, Heidelberg, Germany
[2] Univ Heidelberg Hosp, Neurol Clin, Heidelberg, Germany
[3] Natl Ctr Tumor Dis, Heidelberg, Germany
[4] German Canc Res Ctr, Dept Mol Oncol Gastrointestinal Tumors, Heidelberg, Germany
[5] Univ Heidelberg Hosp, Surg Clin, European Pancreas Ctr, Heidelberg, Germany
关键词
T-CELLS; BLOCKADE; ANTIGENS; MELANOMA;
D O I
10.1038/cr.2015.66
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The efficacy of cancer vaccines has long been hampered by insufficient definition of tumor-specific antigens. A recent study by Kreiter et al. published in Nature has provided a blueprint for a patient-tailored approach to develop individualized RNA vaccines.
引用
收藏
页码:887 / 888
页数:2
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