Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma

被引：3
|
作者：
von Hofsten, Joanna [1 ,2 ]
Ringlander, Johan [3 ]
Norberg, Peter [3 ]
Zetterberg, Madeleine [1 ,4 ]
Andersson, Maria [3 ]
Lindh, Magnus [3 ]
Bergstrom, Tomas [3 ]
机构：
[1] Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Clin Neurosci, Gothenburg, Sweden
[2] Halland Hosp Halmstad, Dept Ophthalmol, S-30185 Halmstad, Sweden
[3] Univ Gothenburg, Inst Biomed, Dept Infect Dis, Gothenburg, Sweden
[4] Sahlgrens Univ Hosp, Dept Ophthalmol, Gothenburg, Sweden
来源：
OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 06期
基金：
英国医学研究理事会;
关键词：
acute retinal necrosis; aqueous humor; high-throughput sequencing; varicella zoster virus;
D O I：
10.1093/ofid/ofaa198
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis.
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页数：4
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