PF11 inhibits microglia-mediated neuroinflammation by inactivating NF-κB, Akt, MAPKs pathways

被引：0
|
作者：
Wang, Xiao-xiao [1 ]
Zhao, Si-qi [1 ]
Wang, Chun-ming [1 ]
Zhang, Wei [1 ]
Zhang, Yu-chen [1 ]
Wu, Chun-fu [1 ]
Yang, Jing-yu [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Dept Pharmacol, Shenyang 110016, Peoples R China
来源：
ACTA PHARMACOLOGICA SINICA | 2013年 / 34卷
关键词：
PF11; microglia; inflammation; NF-kappa B; MAPK;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：134 / 134
页数：1
相关论文
共 50 条
  • [1] Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-κB and ERK Signaling Pathways
    Lai, Nicole Jean-Yean
    Ngu, Ee-Ling
    Pang, Jun-Rui
    Wong, Kah-Hui
    Ardianto, Chrismawan
    Ming, Long Chiau
    Lim, Siew-Huah
    Walvekar, Shweta Gangasa
    Anwar, Ayaz
    Yow, Yoon-Yen
    MARINE DRUGS, 2022, 20 (08)
  • [2] Methionine Sulfoxide Reductase A Negatively Controls Microglia-Mediated Neuroinflammation via Inhibiting ROS/MAPKs/NF-κB Signaling Pathways Through a Catalytic Antioxidant Function
    Fan, Hua
    Wu, Peng-Fei
    Zhang, Ling
    Hu, Zhuang-Li
    Wang, Wen
    Guan, Xin-Lei
    Luo, Han
    Ni, Ming
    Yang, Jing-Wen
    Li, Ming-Xing
    Chen, Jian-Guo
    Wang, Fang
    ANTIOXIDANTS & REDOX SIGNALING, 2015, 22 (10) : 832 - 847
  • [3] Isoliquiritigenin inhibits microglia-mediated neuroinflammation in models of Parkinson's disease via JNK/AKT/NFκB signaling pathway
    Bai, Yuyan
    Zhou, Jin
    Zhu, Han
    Tao, Yanlin
    Wang, Lupeng
    Yang, Liu
    Wu, Hui
    Huang, Fei
    Shi, Hailian
    Wu, Xiaojun
    PHYTOTHERAPY RESEARCH, 2023, 37 (03) : 848 - 859
  • [4] Copper induces microglia-mediated neuroinflammation through ROS/ NF-?B pathway and mitophagy disorder
    Zhou, Qian
    Zhang, Ying
    Lu, Lu
    Zhang, Hu
    Zhao, Chao
    Pu, Yuepu
    Yin, Lihong
    FOOD AND CHEMICAL TOXICOLOGY, 2022, 168
  • [5] Edaravone Alleviates BV-2 Microglia-Mediated Neuroinflammation Through the PI3K/AKT/ NF-κB Pathway
    Yang, Li
    Duan, Zhaoda
    Xu, Dongyao
    Peng, Yingqi
    Wu, Yuke
    Yang, Yujia
    Yin, Qian
    Fang, Lanxi
    Yan, Shan
    Wu, Chunyun
    ADVANCED BIOLOGY, 2025,
  • [6] Dietary flavonoid isoliquiritigenin inhibits microglia-mediated neuroinflammation in Parkinson's disease models via JNK/NFκB/AKT signaling pathway
    Huang, Fei
    Bai, Yuyan
    Zhou, Jin
    Wu, Xiaojun
    PSYCHONEUROENDOCRINOLOGY, 2023, 153 : S23 - S24
  • [7] Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways
    Wang, Xiaoxiao
    Wang, Chunming
    Wang, Jiming
    Zhao, Siqi
    Zhang, Kuo
    Wang, Jingmin
    Zhang, Wei
    Wu, Chunfu
    Yang, Jingyu
    NEUROPHARMACOLOGY, 2014, 79 : 642 - 656
  • [8] Sesquiterpene dimer (DSF-52) from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-κB, JNK/p38 MAPKs and Jak2/Stat3 signaling pathways
    Zeng, Ke-Wu
    Wang, Shu
    Dong, Xin
    Jiang, Yong
    Tu, Peng-Fei
    PHYTOMEDICINE, 2014, 21 (03) : 298 - 306
  • [9] Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α-NF-κB signals
    Huang, Chao
    Wang, Jili
    Lu, Xu
    Hu, Wenfeng
    Wu, Feng
    Jiang, Bo
    Ling, Yong
    Yang, Rongrong
    Zhang, Wei
    NEUROSCIENCE LETTERS, 2016, 619 : 34 - 42
  • [10] Narciclasine inhibits LPS-induced neuroinflammation by modulating the Akt/IKK/NF-κB and JNK signaling pathways
    Zhao, Dong
    Zhang, Li Jun
    Huang, Tian Qi
    Kim, Joonki
    Gu, Ming-Yao
    Yang, Hyun Ok
    PHYTOMEDICINE, 2021, 85
12345