Current State and Future Challenges of Chemoprevention

被引：0

作者：

Davis, Jennifer S. ^{[1
]}

Wu, Xiangwei ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Clin Canc Prevent, Houston, TX 77030 USA

来源：

DISCOVERY MEDICINE | 2012年 / 13卷 / 72期

关键词：

BREAST-CANCER CHEMOPREVENTION; METASTATIC COLORECTAL-CANCER; LUNG-CANCER; HUMAN-PAPILLOMAVIRUS; SYNTHETIC LETHALITY; PROSTATE-CANCER; HEPATOCELLULAR-CARCINOMA; QUADRIVALENT VACCINE; PREVENTION TRIAL; CLINICAL-TRIAL;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

There have been numerous chemoprevention trials in the past 10 years, but the number of approved chemoprevention drugs is still quite small. This is likely due to a number of factors, but two consistent problems in the field of chemoprevention have been the lack of efficacy with or without unacceptable toxicity, and unexpected toxicity or fear of it associated with most of the approaches. This review intends to describe the types of chemoprevention as well as highlight recent successes and failures. We will also discuss potential solutions for the problems of limited efficacy and toxicity. [Discovery Medicine 13(72):385-390, May 2012]

引用

页码：385 / 390

页数：6

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