The impact of rheumatoid arthritis on work capacity in Chinese patients: a cross-sectional study

被引:14
|
作者
Zhang, Xiaoying [1 ]
Mu, Rong [1 ]
Wang, Xiuru [2 ]
Xu, Chuanhui [1 ]
Duan, Tianjiao [3 ]
An, Yuan [1 ]
Han, Shuling [2 ]
Li, Xiaofeng [4 ]
Wang, Lizhi [4 ]
Wang, Caihong [4 ]
Wang, Yongfu [5 ]
Yang, Rong [5 ]
Wang, Guochun [6 ]
Lu, Xin [6 ]
Zhu, Ping [7 ]
Chen, Lina [7 ]
Liu, Jinting [8 ]
Jin, Hongtao [8 ]
Liu, Xiangyuan [9 ]
Sun, Lin [9 ]
Wei, Ping [10 ]
Wang, Junxiang [10 ]
Chen, Haiying [10 ]
Cui, Liufu [11 ]
Shu, Rong [11 ]
Liu, Bailu [11 ]
Zhang, Zhuoli [12 ]
Li, Guangtao [12 ]
Li, Zhenbin [13 ]
Yang, Jing [13 ]
Li, Junfang [14 ]
Jia, Bin [14 ]
Zhang, Fengxiao [15 ]
Tao, Jiemei [15 ]
Lin, Jinying [16 ]
Wei, Meiqiu [16 ]
Liu, Xiaomin [17 ]
Ke, Dan [17 ]
Hu, Shaoxian [18 ]
Ye, Cong [18 ]
Yang, Xiuyan [19 ]
Li, Hao [19 ]
Huang, Cibo [20 ]
Gao, Ming [20 ]
Lai, Pei [20 ]
Li, Xingfu [21 ]
Song, Lijun [21 ]
Wang, Yi [22 ]
Wang, Xiaoyuan [22 ]
Su, Yin [1 ]
机构
[1] Peking Univ, Peoples Hosp, Hlth Sci Ctr, Dept Rheumatol & Immunol, Beijing 100871, Peoples R China
[2] Peking Univ, Shougang Hosp, Dept Rheumatol & Immunol, Beijing 100871, Peoples R China
[3] Peking Univ, Peoples Hosp, Hlth Sci Ctr, Dept Gastroenterol, Beijing 100871, Peoples R China
[4] Shanxi Med Univ, Hosp 2, Dept Rheumatol & Immunol, Taiyuan, Peoples R China
[5] Baotou Med Coll, Affiliated Hosp 1, Dept Rheumatol & Immunol, Baotou, Peoples R China
[6] China Japan Friendship Hosp, Dept Rheumatol, Beijing, Peoples R China
[7] Fourth Mil Med Univ, Xijing Hosp, Dept Clin Immunol, Xian 710032, Peoples R China
[8] Hebei Med Univ, Hosp 2, Dept Rheumatol & Immunol, Shijiazhuang, Peoples R China
[9] Peking Univ, Hosp 3, Dept Rheumatol & Immunol, Beijing 100871, Peoples R China
[10] Hebei Med Univ, Hosp 3, Dept Rheumatol & Immunol, Shijiazhuang, Peoples R China
[11] North China Coal Med Univ, Affiliated Kailuan Hosp, Dept Rheumatol & Immunol, Tangshan, Hebei, Peoples R China
[12] Peking Univ, Hosp 1, Dept Rheumatol & Clin Immunol, Beijing 100871, Peoples R China
[13] Bethune Int Peace Hosp PLA, Dept Rheumatol & Immunol, Shijiazhuang, Peoples R China
[14] Handan Cent Hosp, Dept Rheumatol & Immunol, Handan, Peoples R China
[15] Peoples Hosp Hebei Prov, Dept Rheumatol & Immunol, Shijiazhuang, Peoples R China
[16] Peoples Hosp Guangxi Zhuang Autonomous Reg, Dept Rheumatol, Nanning, Peoples R China
[17] Beijing Shunyi Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China
[18] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Rheumatol, Wuhan 430074, Peoples R China
[19] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Rheumatol, Guangzhou 510275, Guangdong, Peoples R China
[20] Beijing Hosp, Dept Rheumatol & Immunol, Beijing, Peoples R China
[21] Shandong Univ, Qilu Hosp, Dept Rheumatol, Jinan 250100, Peoples R China
[22] Lanzhou Univ, Hosp 2, Deparment Rheumatol, Lanzhou 730000, Peoples R China
关键词
rheumatoid arthritis; work capacity; cross-sectional study; FOLLOW-UP; PREDICTIVE FACTORS; INCEPTION COHORT; DISEASE-ACTIVITY; DISABILITY; RISK; RA; REGISTER; IDENTIFICATION; PRODUCTIVITY;
D O I
10.1093/rheumatology/kev014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective. To evaluate the impact of RA on work capacity and identify factors related to work capacity impairment in patients with RA. Methods. A cross-sectional multicentre study was performed in 21 tertiary care hospitals across China. A consecutive sample of 846 patients with RA was recruited, of which 589 patients of working age at disease onset constituted the study population. Information on the socio-demographic, clinical, working and financial conditions of the patients was collected. Logistic regression analyses were used to identify factors associated with work capacity impairment. Results. The rate of work capacity impairment was 48.0% in RA patients with a mean disease duration of 60 months (interquartile range 14-134 months), including 11.7% leaving the labour force early, 33.6% working reduced hours and 2.7% changing job. Multivariable logistic regression analysis showed that reduced working hours was significantly related to current smoking [odds ratio (OR) 2.07 (95% CI 1.08, 3.97)], no insurance [OR 1.94 (95% CI 1.20, 3.12)], in manual labour [OR 2.66 (95% CI 1.68, 4.20)] and higher HAQ score [OR 2.22 (95% CI 1.36, 3.60)]. There was an association of current smoking [OR 3.75 (95% CI 1.54, 9.15)], in manual labour [OR 2.33 (95% CI 1.17, 4.64)], longer disease duration OR 1.01 (95% CI 1.00, 1.01)] and lower BMI [OR 0.90 (95% CI 0.82, 0.99)] with leaving the labour force early. Conclusion. There is a substantial impact of RA on the work capacity of patients in China. Social-demographic, disease- and work-related factors are all associated with work capacity impairment.
引用
收藏
页码:1478 / 1487
页数:10
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