Fluorescent probes designed for detecting human serum albumin on the basis of its pseudo-esterase activity

被引:26
|
作者
Kim, Sung-Jean [2 ]
Rhee, Hyun-Woo [1 ]
Park, Hyun-Joo [1 ]
Kim, Hye-Yeon [3 ]
Kim, Hyo-Soo [2 ]
Hong, Jong-In [1 ]
机构
[1] Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea
[2] Seoul Natl Univ, Dept Biomed Sci, Seoul 110799, South Korea
[3] Korea Basic Sci Inst, Ochang, South Korea
基金
新加坡国家研究基金会;
关键词
Activity-based probe; Human serum albumin; Esterase; ACUTE MONOCYTIC LEUKEMIA; ACETYLSALICYLIC ACID; PHOSPHATASES; LIBRARY; BINDING;
D O I
10.1016/j.bmcl.2013.01.124
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
We developed activity-based fluorescent probes for detecting human serum albumin (HSA) on the basis of its pseudo-esterase activity. These probes could also detect HSA in blood-contaminated tissue samples. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2093 / 2097
页数:5
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